Measurements of endothelin-1, C-reactive protein and fibrinogen plasma levels in patients with acute ischemic stroke

Απλή σελίδα τεκμηρίου
dc.contributor.authorGiannopoulos, S.en
dc.contributor.authorKosmidou, M.en
dc.contributor.authorHatzitolios, A. I.en
dc.contributor.authorSavopoulos, C. G.en
dc.contributor.authorZiakas, A.en
dc.contributor.authorKaramouzis, M.en
dc.date.accessioned2015-11-24T19:05:09Z
dc.date.available2015-11-24T19:05:09Z
dc.identifier.issn0161-6412-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20152
dc.rightsDefault Licence-
dc.subjectAcute Diseaseen
dc.subjectAgeden
dc.subjectAged, 80 and overen
dc.subjectBiological Markers/analysis/blooden
dc.subjectBrain/metabolism/physiopathology/radiographyen
dc.subjectBrain Ischemia/*blood/*diagnosis/physiopathologyen
dc.subjectC-Reactive Protein/analysis/*metabolismen
dc.subjectEndothelin-1/analysis/*blooden
dc.subjectFemaleen
dc.subjectFibrinogen/analysis/*metabolismen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectPredictive Value of Testsen
dc.subjectRadioimmunoassayen
dc.subjectTomography, X-Ray Computeden
dc.subjectUp-Regulation/physiologyen
dc.titleMeasurements of endothelin-1, C-reactive protein and fibrinogen plasma levels in patients with acute ischemic strokeen
heal.abstractOBJECTIVE: To assess plasma endothelin-1 (ET-1), C-reactive protein (CRP) and fibrinogen (FIB) levels in acute ischemic stroke (AIS) and explore the potential association among them. METHODS: In 23 consecutive patients with AIS diagnosed clinically and confirmed by CT brain scan, we measured plasma levels of ET-1 by radioimmunoassay, and CRP and FIB on the first and fifth days after the onset of AIS and we compared them with the levels of ten healthy volunteers in the control group. RESULTS: The mean plasma levels of ET-1 in AIS patients on the first and fifth days were respectively 19.93+/-6.72 and 16.47+/-26.3 pmol/l (p<0.001) compared with 3.68+/-1.2 pmol/l in the control group (p<0.001 versus mean values on the first and fifth days). The mean plasma levels of CRP in the patients on the first and fifth days were respectively 2.7+/-4.7 and 3.0+/-4.4 mg/dl (p>0.05) compared with 0.2+/-0.1 mg/dl in the control group (p<0.05 versus mean values on the first and fifth days). The mean plasma levels of FIB in the patients on the first and fifth days were respectively 361+/-98.89 and 392.7+/-144.89 mg/dl, while in the control group, it was 330.5+/-90.28 mg/dl (p>0.05 versus mean values on the first and fifth days). A positive association was found between the plasma levels of ET-1 and CRP on the fifth day (p<0.05). CONCLUSIONS: ET-1 was found to be significantly elevated in the plasma in the AIS. There is association between ET-1 and CRP on the fifth day after AIS. Plasma levels of ET-1 and its association with CRP levels may be used as additional biomarkers for AIS.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1179/174313208X297904-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18489822-
heal.journalNameNeurol Resen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

Αρχεία

Φάκελος/Πακέτο αδειών

Προβολή: 1 - 1 of 1
Μικρογραφία εικόνας
Ονομα:
license.txt
Μέγεθος:
1.74 KB
Μορφότυπο:
Item-specific license agreed upon to submission
Περιγραφή:
Κατεβάστε

Συλλογές

Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ