Distinct association of SLC19A1 polymorphism -43T>C with red cell folate levels and of MTHFR polymorphism 677C>T with plasma folate levels

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dc.contributor.authorChatzikyriakidou, A.en
dc.contributor.authorVakalis, K. V.en
dc.contributor.authorKolaitis, N.en
dc.contributor.authorKolios, G.en
dc.contributor.authorNaka, K. K.en
dc.contributor.authorMichalis, L. K.en
dc.contributor.authorGeorgiou, I.en
dc.date.accessioned2015-11-24T19:24:07Z
dc.date.available2015-11-24T19:24:07Z
dc.identifier.issn0009-9120-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22420
dc.rightsDefault Licence-
dc.subject5-Methyltetrahydrofolate-Homocysteine S-Methyltransferase/blood/geneticsen
dc.subjectBiological Markers/blooden
dc.subjectCoronary Artery Disease/blood/geneticsen
dc.subjectErythrocytes/chemistry/*metabolismen
dc.subjectFemaleen
dc.subjectFolic Acid/*blood/geneticsen
dc.subjectFolic Acid Deficiency/blood/geneticsen
dc.subjectGenetic Predisposition to Diseaseen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMembrane Transport Proteins/blood/*geneticsen
dc.subjectMethylenetetrahydrofolate Reductase (NADPH2)/blood/*geneticsen
dc.subjectMiddle Ageden
dc.subjectPolymorphism, Single Nucleotide/*geneticsen
dc.subjectReduced Folate Carrier Proteinen
dc.subjectSerum/chemistry/*metabolismen
dc.titleDistinct association of SLC19A1 polymorphism -43T>C with red cell folate levels and of MTHFR polymorphism 677C>T with plasma folate levelsen
heal.abstractOBJECTIVES: The role of SLC19A1 -43T>C, MTHFR 677C>T and MS 2756A>G polymorphisms on red cell and plasma folate levels. DESIGN AND METHODS: Genotype analysis of the three polymorphisms. Red cell and plasma folate measurements in 64 patients with coronary artery disease. RESULTS: The non-wild type allele of SLC19A1 polymorphism -43T>C was associated with low red cell folate levels and the non-wild type allele of MTHFR polymorphism 677C>T with low plasma folate levels. CONCLUSION: SLC19A1 and MTHFR genes are differently associated with red cell and plasma folate levels.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.clinbiochem.2007.11.006-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18053808-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0009912007004432/1-s2.0-S0009912007004432-main.pdf?_tid=512033f4db955353f409eb8a7fed56c2&acdnat=1333347616_21015e785c792752761751acab7dbab3-
heal.journalNameClin Biochemen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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