Lipid profile, glucose homeostasis, blood pressure, and obesity-anthropometric markers in macrosomic offspring of nondiabetic mothers

Απλή σελίδα τεκμηρίου
dc.contributor.authorEvagelidou, E. N.en
dc.contributor.authorKiortsis, D. N.en
dc.contributor.authorBairaktari, E. T.en
dc.contributor.authorGiapros, V. I.en
dc.contributor.authorCholevas, V. K.en
dc.contributor.authorTzallas, C. S.en
dc.contributor.authorAndronikou, S. K.en
dc.date.accessioned2015-11-24T19:06:58Z
dc.date.available2015-11-24T19:06:58Z
dc.identifier.issn0149-5992-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20393
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectBirth Weighten
dc.subjectBlood Glucose/*metabolismen
dc.subject*Blood Pressureen
dc.subjectBody Heighten
dc.subjectBody Sizeen
dc.subjectBody Weighten
dc.subjectChild, Preschoolen
dc.subjectFemaleen
dc.subjectFetal Macrosomia/blood/*physiopathologyen
dc.subjectGestational Ageen
dc.subjectHumansen
dc.subjectInfanten
dc.subjectLipids/*blooden
dc.subjectMaternal Ageen
dc.subjectObesity/*epidemiologyen
dc.subjectSkinfold Thicknessen
dc.titleLipid profile, glucose homeostasis, blood pressure, and obesity-anthropometric markers in macrosomic offspring of nondiabetic mothersen
heal.abstractOBJECTIVE: The study was to determine whether being the macrosomic offspring of a mother without detected glucose intolerance during pregnancy has an impact on lipid profile, glucose homeostasis, and blood pressure during childhood. RESEARCH DESIGN AND METHODS: Plasma total, HDL, and LDL cholesterol; triglycerides; apolipoprotein (Apo) A-1, -B, and -E; lipoprotein (a); fasting glucose and insulin; homeostasis model assessment of insulin resistance (HOMA-IR) index; blood pressure; BMI; and detailed anthropometry were evaluated in 85 children aged 3-10 years old, born appropriate for gestational age (AGA; n = 48) and large for gestational age (LGA; n = 37) of healthy mothers. RESULTS: At the time of the assessment, body weight, height, skinfold thickness, BMI, waist circumference, and blood pressure did not differ between the LGA and AGA groups with the exception of head circumference (P < 0.01). There were no significant differences in plasma total or LDL cholesterol; triglycerides; Apo A-1, -B, or -E; lipoprotein (a); Apo B-to-Apo A-1 ratio; or glucose levels between the groups. The LGA group had significantly higher HDL cholesterol levels (P < 0.01), fasting insulin levels (P < 0.01), and HOMA-IR index (P < 0.01) but lower values of the glucose-to-insulin ratio (P < 0.01) as compared with the AGA group. CONCLUSIONS: Children born LGA of mothers without confirmed impaired glucose tolerance during pregnancy show higher insulin concentrations than AGAs.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.2337/dc05-2401-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/16731995-
heal.identifier.secondaryhttp://care.diabetesjournals.org/content/29/6/1197.full.pdf-
heal.journalNameDiabetes Careen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2006-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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