Thiamine models and perspectives on the mechanism of action of thiamine-dependent enzymes
| dc.contributor.author | Malandrinos, G. | en |
| dc.contributor.author | Louloudi, M. | en |
| dc.contributor.author | Hadjiliadis, N. | en |
| dc.date.accessioned | 2015-11-24T16:51:34Z | |
| dc.date.available | 2015-11-24T16:51:34Z | |
| dc.identifier.issn | 0306-0012 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/9752 | |
| dc.rights | Default Licence | - |
| dc.subject | 2-(alpha-hydroxyethyl)thiamin pyrophosphate hetpp | en |
| dc.subject | yeast pyruvate decarboxylase | en |
| dc.subject | site-directed mutagenesis | en |
| dc.subject | acid-base groups | en |
| dc.subject | asn-lys-ile | en |
| dc.subject | crystal-structure | en |
| dc.subject | saccharomyces-cerevisiae | en |
| dc.subject | angstrom resolution | en |
| dc.subject | metal-complexes | en |
| dc.subject | benzoylformate decarboxylase | en |
| dc.title | Thiamine models and perspectives on the mechanism of action of thiamine-dependent enzymes | en |
| heal.abstract | Thiamine dependent enzymes catalyze ligase and lyase reactions near a carbonyl moiety. Chemical models for these reactions serve as useful tools to substantiate a detailed mechanism of action. This tutorial review covers all such studies performed thus far, emphasizing the role of each part around the active site and the conformation of the cofactor during catalysis. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | Doi 10.1039/B514511m | - |
| heal.identifier.secondary | <Go to ISI>://000239211500002 | - |
| heal.identifier.secondary | http://pubs.rsc.org/en/content/articlepdf/2006/cs/b514511m | - |
| heal.journalName | Chemical Society Reviews | en |
| heal.journalType | peer reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2006 | - |
| heal.publisher | Royal Society of Chemistry | en |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείας | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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