Epsilon-like waves and ventricular conduction abnormalities in subjects with type 1 ECG pattern of Brugada syndrome

Απλή σελίδα τεκμηρίου
dc.contributor.authorLetsas, K. P.en
dc.contributor.authorEfremidis, M.en
dc.contributor.authorWeber, R.en
dc.contributor.authorKorantzopoulos, P.en
dc.contributor.authorProtonotarios, N.en
dc.contributor.authorPrappa, E.en
dc.contributor.authorKounas, S. P.en
dc.contributor.authorEvagelidou, E. N.en
dc.contributor.authorXydonas, S.en
dc.contributor.authorKalusche, D.en
dc.contributor.authorSideris, A.en
dc.contributor.authorArentz, T.en
dc.date.accessioned2015-11-24T19:18:45Z
dc.date.available2015-11-24T19:18:45Z
dc.identifier.issn1556-3871-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/21895
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectBrugada Syndrome/chemically induced/diagnosis/*physiopathologyen
dc.subjectElectrocardiography/*drug effectsen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHeart Conduction System/drug effects/*physiopathologyen
dc.subjectHeart Ventricles/drug effects/*innervation/physiopathologyen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectRetrospective Studiesen
dc.subjectSodium Channel Blockers/*adverse effectsen
dc.subjectVentricular Function, Right/drug effects/*physiologyen
dc.titleEpsilon-like waves and ventricular conduction abnormalities in subjects with type 1 ECG pattern of Brugada syndromeen
heal.abstractBACKGROUND: Previous studies have demonstrated an overlap between the arrhythmogenic right ventricular cardiomyopathy/dysplasia (ARVC/D) and Brugada syndrome (BS). Conduction delay in the right ventricle has been demonstrated in both entities. OBJECTIVE: This study investigated specific ARVC/D electrocardiographic (ECG) markers in subjects with spontaneous or drug-induced type 1 ECG pattern of BS. METHODS: The study population consisted of 47 apparently healthy individuals (38 men, mean age 44.1 +/- 13.3 years) with spontaneous (n = 17) or drug-induced (n = 30) type 1 ECG phenotype of BS. The clinical records of these individuals were retrospectively analyzed. RESULTS: Fifteen subjects (31.9%) were symptomatic, with a history of syncope. A family history of BS or sudden cardiac death was reported in 10 (21.3%) and 8 (17.0%) cases, respectively. Epsilon-like waves in leads V1-V3 were observed in 6 subjects (12.7%). Epsilon-like waves were seen in spontaneous type 1 ECGs in 2 cases and after sodium channel blocking test in 4 cases. In baseline ECGs, localized prolongation (>110 ms) of the QRS complex in leads V1-V3, QRS duration ratio in (V1+V2+V3)/(V4+V5+V6) >/= 1.2, and prolonged S wave upstroke (>55 ms) in leads V1-V3 were seen in 48.8%, 29.8%, and 40.4% of subjects, respectively. Epsilon-like waves and delayed S wave upstroke were more commonly observed in subjects with family history of BS (P = .014 and P = .038, respectively). CONCLUSION: Specific ECG markers that reflect ventricular conduction delay in ARVC/D are commonly observed in subjects with spontaneous or drug-induced type 1 ECG pattern of BS as well. These depolarization abnormalities may be related to subtle underlying structural abnormalities.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.hrthm.2011.01.043-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21315837-
heal.identifier.secondaryhttp://ac.els-cdn.com/S1547527111001354/1-s2.0-S1547527111001354-main.pdf?_tid=a43f145d5f20a62ea5bc95edf22b486c&acdnat=1333963994_b815f28a11a35709e77f051e9328921f-
heal.journalNameHeart Rhythmen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2011-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

Αρχεία

Φάκελος/Πακέτο αδειών

Προβολή: 1 - 1 of 1
Μικρογραφία εικόνας
Ονομα:
license.txt
Μέγεθος:
1.74 KB
Μορφότυπο:
Item-specific license agreed upon to submission
Περιγραφή:
Κατεβάστε

Συλλογές

Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ