Development of a method for the simultaneous determination of phosphoric and amino acid group containing pesticides by gas chromatography with mass-selective detection - Optimization of the derivatization procedure using an experimental design approach

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dc.contributor.authorStalikas, C. D.en
dc.contributor.authorPilidis, G. A.en
dc.date.accessioned2015-11-24T16:55:59Z
dc.date.available2015-11-24T16:55:59Z
dc.identifier.issn0021-9673-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10377
dc.rightsDefault Licence-
dc.subjectexperimental designen
dc.subjectcentral composite designen
dc.subjectchemometricsen
dc.subjectderivatization, gcen
dc.subjectmethod developmenten
dc.subjectoptimizationen
dc.subjectpesticidesen
dc.subjectorganophosphorus compoundsen
dc.subjectcolumn liquid-chromatographyen
dc.subject(aminomethyl)phosphonic aciden
dc.subjectaminomethylphosphonic aciden
dc.subjectherbicides glyphosateen
dc.subjectrapid-determinationen
dc.subjectglufosinateen
dc.subjectwateren
dc.subjectsamplesen
dc.subjectresiduesen
dc.subjectsimplexen
dc.titleDevelopment of a method for the simultaneous determination of phosphoric and amino acid group containing pesticides by gas chromatography with mass-selective detection - Optimization of the derivatization procedure using an experimental design approachen
heal.abstractAn integrated gas chromatographic-mass-selective detection method for the analysis of the phosphoric and amino acid group containing pesticides is presented. The analytes are derivatized using a single-step procedure for the simultaneous esterification and acetylation of the active groups of analytes (-OH, -COOH, -NH2) by means of acetic acid and trimethyl orthoacetate. An experimental design approach based on the central composite design is used to investigate the dependence of the derivatization variables with the total yield of derivatization of pesticides. The variables selected for study were: the amount of reagents, the temperature and the reaction time. When considering the total pesticide derivatization yield, the amount of acetic acid, the reaction temperature and the reaction time are found to be statistically significant. The electron impact ionization mass spectra of the resulting derivatives are acquired and properly interpreted. Under the chromatographic conditions employed, acceptable peak separation is attained. When the selective ion monitoring mode is used for quantitation purposes, low detection limits in the range 0.05 to 14 mu g/l are achieved. Recoveries of spiked water samples range from 96 to 103% and the mean RSD of the method do not exceed 3.5%. (C) 2000 Elsevier Science B.V. All rights reserved.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/S0021-9673(99)01300-X-
heal.identifier.secondary<Go to ISI>://000085807800017-
heal.identifier.secondaryhttp://ac.els-cdn.com/S002196739901300X/1-s2.0-S002196739901300X-main.pdf?_tid=6eaa477d8d75ea426e42148a7941aeaa&acdnat=1333041025_fea3b64b9d0257dcbbdb440748d1eb78-
heal.journalNameJournal of Chromatography Aen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2000-
heal.publisherElsevieren
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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