Prevention of chemotherapy-induced alopecia using an effective scalp cooling system
Φόρτωση...
Ημερομηνία
Συγγραφείς
Katsimbri, P.
Bamias, A.
Pavlidis, N.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Eur J Cancer
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Alopecia is a distressing side-effect of cancer treatment. Taxanes (TX), anthracyclines (ANR) and etoposide (ET) have been consistently associated with significant alopecia. We studied an effective scalp cooling system, the Penguin Cold Cap system, for the prevention of chemotherapy-induced alopecia in 70 patients receiving chemotherapy, including one of the following major alopecia-causing agents: Group A, TX-based regimes (without ANR); Group B, TX+ANR; Group C, ANR-based regimes (without TX); Group D, ET-based regimes. Protection from hair loss was achieved by maintaining scalp temperatures below 15 degrees C before, during and after chemotherapy by frequent changing of the caps. Assessment was carried out using a grading system from 0 to 4. Grades 0-2 were considered as satisfactory hair protection, whilst Grades 3-4 were considered failures. 57 patients were evaluable for assessment. An overall 81% protection was achieved. In groups C and D 11 of 12 patients (92%) had no alopecia, whilst 30 of 34 patients (88%) treated with taxanes had adequate hair protection. In Group B, 4 of 11 patients (36%) had adequate hair protection. The system was well tolerated and is a very effective method for protection from hair loss caused by TX, ANR and ET. Our results are comparable with and, in most cases, better than those reported in other studies using various alopecia preventive methods.
Περιγραφή
Λέξεις-κλειδιά
Adult, Aged, Alopecia/chemically induced/*prevention & control, Antibiotics, Antineoplastic/adverse effects, Antineoplastic Combined Chemotherapy Protocols/*adverse effects, Cryotherapy/*methods, Etoposide/adverse effects, Female, Humans, Male, Middle Aged, Neoplasms/*drug therapy, Paclitaxel/adverse effects/analogs & derivatives, *Scalp, *Taxoids
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/10762750
http://ac.els-cdn.com/S0959804900000125/1-s2.0-S0959804900000125-main.pdf?_tid=701163203b67c83015e157c1aad6a6fc&acdnat=1333611886_e982cd4b40a6e9e4730fe4e0d594d1a4
http://ac.els-cdn.com/S0959804900000125/1-s2.0-S0959804900000125-main.pdf?_tid=701163203b67c83015e157c1aad6a6fc&acdnat=1333611886_e982cd4b40a6e9e4730fe4e0d594d1a4
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής