Physical and biophysical properties of proton tracks of energies 1 keV to 300 MeV in water
| dc.contributor.author | Liamsuwan, T. | en |
| dc.contributor.author | Uehara, S. | en |
| dc.contributor.author | Emfietzoglou, D. | en |
| dc.contributor.author | Nikjoo, H. | en |
| dc.date.accessioned | 2015-11-24T18:58:34Z | |
| dc.date.available | 2015-11-24T18:58:34Z | |
| dc.identifier.issn | 1362-3095 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19292 | |
| dc.rights | Default Licence | - |
| dc.subject | Algorithms | en |
| dc.subject | Biophysics | en |
| dc.subject | Computer Simulation | en |
| dc.subject | Electrons | en |
| dc.subject | *Models, Theoretical | en |
| dc.subject | *Monte Carlo Method | en |
| dc.subject | *Protons | en |
| dc.subject | Radiometry | en |
| dc.subject | Scattering, Radiation | en |
| dc.subject | *Water | en |
| dc.title | Physical and biophysical properties of proton tracks of energies 1 keV to 300 MeV in water | en |
| heal.abstract | PURPOSE: To investigate physical and biophysical properties of proton tracks 1 keV-300 MeV using Monte Carlo track structure methods. MATERIALS AND METHODS: We present model calculations for cross sections and methods for simulations of full-slowing-down proton tracks. Protons and electrons were followed interaction-by-interaction to cut-off energies, considering elastic scattering, ionisation, excitation, and charge-transfer. RESULTS: Model calculations are presented for singly differential and total cross sections, and path lengths and stopping powers as a measure of the code evaluation. Depth-dose distributions for 160 MeV protons are compared with experimental data. Frequencies of energy loss by electron interactions increase from approximately 3% for 10 keV to approximately 77% for 300 MeV protons, and electrons deposit >70% of the dose in 160 MeV tracks. From microdosimetry calculations, 1 MeV protons were found to be more effective than 5-300 MeV in energy depositions greater than 25, 50, and 500 eV in cylinders of diameters and lengths 2, 10, and 100 nm, respectively. For lower-energy depositions, higher-energy protons are more effective. Decreasing the target size leads to the reduction of frequency- and dose-mean lineal energies for protons <1 MeV, and conversely for higher-energy protons. CONCLUSIONS: Descriptions of proton tracks at molecular levels facilitate investigations of track properties, energy loss, and microdosimetric parameters for radiation biophysics, radiation therapy, and space radiation research. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.3109/09553002.2010.518204 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/21281230 | - |
| heal.identifier.secondary | http://informahealthcare.com/doi/abs/10.3109/09553002.2010.518204 | - |
| heal.journalName | Int J Radiat Biol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2011 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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