Do we reperfuse those in most need? Clinical characteristics of ST-elevation myocardial infarction patients receiving reperfusion therapy in the countrywide registry HELIOS

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dc.contributor.authorPipilis, A.en
dc.contributor.authorAndrikopoulos, G.en
dc.contributor.authorLekakis, J.en
dc.contributor.authorGotsis, A.en
dc.contributor.authorOikonomou, K.en
dc.contributor.authorToli, K.en
dc.contributor.authorKyrpizidis, C.en
dc.contributor.authorLambropoulos, S.en
dc.contributor.authorStefanatos, L.en
dc.contributor.authorGoumas, G.en
dc.contributor.authorKochiadakis, G.en
dc.contributor.authorKoutsogiannis, N.en
dc.contributor.authorKassimatis, A.en
dc.contributor.authorKogias, I.en
dc.contributor.authorKartalis, A.en
dc.contributor.authorKostopoulos, V.en
dc.contributor.authorGoudevenos, J.en
dc.contributor.authorHelios Groupen
dc.date.accessioned2015-11-24T19:23:57Z
dc.date.available2015-11-24T19:23:57Z
dc.identifier.issn1109-9666-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22391
dc.rightsDefault Licence-
dc.subjectAngioplasty, Balloon, Coronaryen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectMyocardial Infarction/diagnosis/mortality/*therapyen
dc.subject*Myocardial Reperfusionen
dc.subjectRegistriesen
dc.subjectThrombolytic Therapyen
dc.titleDo we reperfuse those in most need? Clinical characteristics of ST-elevation myocardial infarction patients receiving reperfusion therapy in the countrywide registry HELIOSen
heal.abstractINTRODUCTION: we analysed the clinical profile of patients with an ST-elevation myocardial infarction (STEMI) who arrived in hospital within 12 hrs from pain onset and either received reperfusion therapy (PCI or fibrinolytic therapy) or remained without reperfusion. METHODS: the Hellenic Infarction Observation Study (HELIOS) was a countrywide registry of acute myocardial infarction, conducted during 2005-2006. The registry enrolled 1840 patients with myocardial infarction from 31 hospitals, with a proportional representation of all types of hospitals and all geographical areas. RESULTS: of 870 patients with STEMI who were admitted within 12 hrs from pain onset, Group A received no reperfusion (n=289, 33.2%), group B underwent primary PCI (n=84, 9.7%) and group C received fibrinolysis (n=497, 57.1%). In groups A, B and C, respectively, mean age was 73 +/- 13, 61 +/- 12 and 62 +/- 13 years (p<0.001). The prevalence of female sex was 33%, 14%, 18%, of diabetes 40%, 23%, 21%, of prior MI 23%, 10%, 11% and of Killip class 2-4 at admission 32%, 11%, 13%, respectively (all p<0.001). In a multivariate analysis, advanced Killip class, age, diabetes and pain to admission time >3 hrs were all independent variables related to no reperfusion therapy. CONCLUSION: reperfusion therapies are applied to relatively lower-risk patients. If a survival advantage is to be expected at the national level, more high-risk patients, such as the elderly, women, diabetics, and mainly those with advanced Killip class, should be considered for reperfusion strategies.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21169180-
heal.journalNameHellenic J Cardiolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2010-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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