Meta-analysis methods
| dc.contributor.author | Trikalinos, T. A. | en |
| dc.contributor.author | Salanti, G. | en |
| dc.contributor.author | Zintzaras, E. | en |
| dc.contributor.author | Ioannidis, J. P. | en |
| dc.date.accessioned | 2015-11-24T19:04:45Z | |
| dc.date.available | 2015-11-24T19:04:45Z | |
| dc.identifier.issn | 0065-2660 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20097 | |
| dc.rights | Default Licence | - |
| dc.subject | *Genetic Techniques | en |
| dc.subject | Humans | en |
| dc.subject | *Meta-Analysis as Topic | en |
| dc.subject | Models, Genetic | en |
| dc.title | Meta-analysis methods | en |
| heal.abstract | Meta-analysis is the quantitative synthesis of information from several studies. It is applicable to a variety of study designs in genetics, from family-based linkage studies and population-based association studies to genome-wide scans and genome-wide association studies. By combining relevant evidence from many studies, statistical power is increased and more precise estimates may be obtained. Most importantly, meta-analysis provides a framework for the appreciation and assessment of between-study heterogeneity, that is, the methodological, epidemiological, clinical, and biological dissimilarity across the various studies. Being a retrospective research design in most cases, meta-analysis is subject to a variety of selection biases that may undermine its validity. A major challenge is to differentiate genuine between-study heterogeneity from systematic errors and biases. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1016/S0065-2660(07)00413-0 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18358326 | - |
| heal.identifier.secondary | http://ac.els-cdn.com/S0065266007004130/1-s2.0-S0065266007004130-main.pdf?_tid=9732bbad7035c9f645219a074a19644e&acdnat=1333018220_15a90d57c9f62b2c6eb50abb01cb5d07 | - |
| heal.journalName | Adv Genet | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2008 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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