On the mechanism of action of thiamin enzymes in the presence of bivalent metal ions

dc.contributor.authorMalandrinos, G.en
dc.contributor.authorDodi, K.en
dc.contributor.authorLouloudi, M.en
dc.contributor.authorHadjiliadis, N.en
dc.date.accessioned2015-11-24T16:43:12Z
dc.date.available2015-11-24T16:43:12Z
dc.identifier.issn0162-0134-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/8667
dc.rightsDefault Licence-
dc.subjectthiamin enzymesen
dc.subjectbivalent metal ionsen
dc.subjectdiphosphate dependent enzymeen
dc.subjectcrystal-structureen
dc.subjectchloride hydrochlorideen
dc.subjectaldehyde derivativesen
dc.subjectangstrom resolutionen
dc.subjectcomplexesen
dc.subjectcatalysisen
dc.subject2-(alpha-hydroxybenzyl)thiamineen
dc.subjectstereochemistryen
dc.subjectdecarboxylaseen
dc.titleOn the mechanism of action of thiamin enzymes in the presence of bivalent metal ionsen
heal.abstractResults on the interactions between the bivalent metal ions Zn2+, Cd2+, Hg2+, Co2+, Ni-2 and 'active aldehyde' thiamin derivatives are reviewed. The techniques used in these studies include spectroscopic methods, i.e., IR-Raman, UV-Vis, multidimensional and multinuclear NMR in solution and in solid state, and X-ray crystal structure determinations. More recently, potentiometric studies on thiamin pyrophosphate and 2-(alpha-hydroxyethyl)thiamin in combination with NMR and EPR techniques were also undertaken. All these studies lead to useful conclusions on the mechanism of action of thiamin enzymes in the presence of bivalent metal ions. (C) 2000 EIsevier Science Inc. All rights reserved.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDoi 10.1016/S0162-0134(99)00178-6-
heal.identifier.secondary<Go to ISI>://000086988500005-
heal.identifier.secondaryhttp://ac.els-cdn.com/S0162013499001786/1-s2.0-S0162013499001786-main.pdf?_tid=846052ae7bff31621e18400b587fad19&acdnat=1333034404_2dfc9e9c0c1e9995369c7fdf1de4bd91-
heal.journalNameJ Inorg Biochemen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2000-
heal.publisherElsevieren
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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