Conditional evaluation of broncho-alveolar lavage in mechanically ventilated patients with suspected unilateral lobar pneumonia

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dc.contributor.authorPrekates, A.en
dc.contributor.authorNanas, S.en
dc.contributor.authorNakos, G.en
dc.contributor.authorFloros, J.en
dc.contributor.authorArgyropoulou, A.en
dc.contributor.authorPaniara, O.en
dc.contributor.authorRoussos, C.en
dc.date.accessioned2015-11-24T19:27:50Z
dc.date.available2015-11-24T19:27:50Z
dc.identifier.issn0256-9574-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22849
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAnti-Bacterial Agents/therapeutic useen
dc.subjectBronchoalveolar Lavage/*methodsen
dc.subjectBronchoalveolar Lavage Fluid/*microbiologyen
dc.subjectBronchoscopyen
dc.subjectEvaluation Studies as Topicen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLung/microbiologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPneumonia, Pneumococcal/*diagnosis/drug therapy/etiology/microbiologyen
dc.subjectProspective Studiesen
dc.subjectRespiration, Artificial/*adverse effectsen
dc.titleConditional evaluation of broncho-alveolar lavage in mechanically ventilated patients with suspected unilateral lobar pneumoniaen
heal.abstractOBJECTIVE: In an attempt to improve our ability to diagnose the cause of ventilator-associated pneumonia (VAP), we explore the usefulness of the conditional evaluation of bronchoalveolar lavage (BAL) samples from the involved and non-involved areas in patients with suspected unilateral lobar VAP (UL-VAP). DESIGN: Prospective study. SETTING: University teaching hospital intensive care unit. PATIENTS: We studied 19 consecutive patients with suspected UL-VAP. MEASUREMENTS AND MAIN RESULTS: Nine of the 12 patients (47%) developed UL-VAP. There was a significant difference between the involved and non-involved areas in UL-VAP patients (P < 0.001) in respect of the quantitative bacterial cultures (QBCs) of BAL samples for each micro-organism, whereas there was no difference in patients without UL-VAP. When we applied the criterion of usual BAL (one micro-organism in concentrations > 10(5) colony-forming units per millilitre) for UL-VAP diagnosis, the sensitivity was 100%, the specificity 70%, the positive predictive value 75%, and the negative predictive value 100%. When we used the conditional evaluation of the BAL results for UL-VAP diagnosis, in the involved and non-involved areas, the sensitivity was 78%, the specificity 90%, the positive predictive value 87.5% and the negative predictive value 82%. A statistically significant difference was found when we compared the difference in QBCs between the BAL samples for each micro-organism, between the involved and non-involved areas in patients with and without VAP (P < 0.001). CONCLUSION: These data suggest that utilisation of the conditional evaluation of the QBCs of BAL samples improves significantly our ability to diagnose the cause of UL-VAP.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9180832-
heal.journalNameS Afr Med Jen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1997-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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