Micro- and macro-consequences of ooplasmic injections of early haploid male gametes

dc.contributor.authorSofikitis, N.en
dc.contributor.authorMiyagawa, I.en
dc.contributor.authorYamamoto, Y.en
dc.contributor.authorLoutradis, D.en
dc.contributor.authorMantzavinos, T.en
dc.contributor.authorTarlatzis, V.en
dc.date.accessioned2015-11-24T19:04:27Z
dc.date.available2015-11-24T19:04:27Z
dc.identifier.issn1355-4786-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20044
dc.rightsDefault Licence-
dc.subjectAnimalsen
dc.subjectCytoplasmen
dc.subjectFemaleen
dc.subjectFertilization in Vitro/*methodsen
dc.subject*Haploidyen
dc.subjectHumansen
dc.subjectMaleen
dc.subject*Microinjectionsen
dc.subjectNuclear Transfer Techniquesen
dc.subjectOligospermia/therapyen
dc.subjectOocytes/*ultrastructureen
dc.subject*Spermatids/ultrastructureen
dc.subjectSpermatogenesisen
dc.subjectZygoteen
dc.titleMicro- and macro-consequences of ooplasmic injections of early haploid male gametesen
heal.abstractThis review refers to the evolution of ooplasmic injections of round spermatid nuclei (ROSNI) or intact round spermatids (ROSI). Conclusions from their preliminary application in the hamster, rabbit, mouse and human are discussed. Criteria for identification of round spermatids and guidelines/quality control for application of ROSNI/ROSI techniques are emphasized. Although all the animal offspring and the human newborns delivered after ROSNI/ROSI are healthy, additional research efforts are necessary to confirm the safety of these procedures and improve their outcome.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/9741705-
heal.identifier.secondaryhttp://humupd.oxfordjournals.org/content/4/3/197.full.pdf-
heal.journalNameHum Reprod Updateen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1998-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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