Φλεγμονώδης πάθηση των εντέρων
| dc.contributor.author | Νταλέκος, Γεώργιος Ν. | el |
| dc.date.accessioned | 2015-10-18T10:35:06Z | |
| dc.date.available | 2015-10-18T10:35:06Z | |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/939 | |
| dc.identifier.uri | http://dx.doi.org/10.26268/heal.uoi.1034 | |
| dc.rights | Default License | |
| dc.subject | Αντισώματα κατά κυτταροπλάσματος ουδετεροφίλων | el |
| dc.subject | Διάλυτοι υποδοχείς ιντερλευκίνης-2 | el |
| dc.subject | Ελκώδης κολίτιδα | el |
| dc.subject | Ιντερλευκίνες | el |
| dc.subject | Κυτταροκίνες | el |
| dc.subject | Νόσος Crohn | el |
| dc.subject | Φλεγμονώδεις πάθηση των εντέρων | el |
| dc.title | Φλεγμονώδης πάθηση των εντέρων | el |
| heal.abstract | THE PRESENT STUDY HAD TWO AIMS. FIRST, TO INVESTIGATE FOR A POSSIBLE AUTOIMMUNERESPONSE IN PATIENTS WITH ULCERATIVE COLITIS AS WELL AS, THE PRESENCE OF CELLULAR IMMUNE ACTIVATION BY DETECTING THE SOLUBLE INTERLEUKIN-2 RECEPTORS (SIL-2RS) LEVELS. SECOND, TO STUDY THE PRESENCE OF SEVERAL CYTOKINES IN THESE PATIENTS. IN THE FIRST PART, IT WAS FOUND THAT ULCERATIVE COLITIS IS ACCOMPANIEDBY AN AUTOIMMUNE RESPONSE (76.3% AUTOANTIBODIES OF AT LEAST ONE SPECIFICITY)AND INCREASED CELLULAR IMMUNE ACTIVATION (HIGH SIL-2R CONCENTRATIONS). THESEFINDINGS WERE CONFIRMED IN PAIRED SERUM SAMPLES TAKEN FROM 10 PATIENTS DURING ACTIVE DISEASE AND AFTER UNDERGOING A CLINICAL REMISSION AND RELATED WITH THE ACTIVITY OF THE DISEASE. IN THE SECOND PART, IT WAS FOUND THAT ULCERATIVE COLITIS IS ALSO ACCOMPANIED BY HIGH INTERLEUKIN-6 (IL-6) LEVELS WHICH CORRELATED WITH THE ACTIVITY OF THE DISEASE. THESE MARKERS (SIL-2RS, IL-6) APPEAR TO BE THE MOST USEFUL LABORATORY INDICATORS FOR ASSESSING THE ACTIVITY OF ULCERATIVE COLITIS. NO OTHER CYTOKINE HAS BEEN DETECTED IN THE SYSTEMIC CIRCULATIONOF THE PATIENTS WITH ULCERATIVE COLITIS. | en |
| heal.academicPublisher | Πανεπιστήμιο Ιωαννίνων Σχολή Ιατρικής Τμήμα Ιατρικής | el |
| heal.academicPublisherID | uoi | |
| heal.access | free | |
| heal.advisorName | - | |
| heal.bibliographicCitation | Βιβλιογραφία: σ. 103 - 169 | el |
| heal.classification | Έντερα | el |
| heal.classification | Ασθένειες | el |
| heal.classification | Ανοσολογία | el |
| heal.committeeMemberName | Τσιάνος, Επαμεινώνδας | el |
| heal.committeeMemberName | Σκοπούλη, Φωτεινή | el |
| heal.committeeMemberName | Σιαμοπούλου - Μαυρίδου, Αντιγόνη | el |
| heal.committeeMemberName | Μουτσόπουλος, Χαράλαμπος | el |
| heal.committeeMemberName | Παγουλάτος, Γεράσιμος | el |
| heal.committeeMemberName | Αγνάντη, Νίκη | el |
| heal.committeeMemberName | Δρόσος, Αλέξανδρος | el |
| heal.fullTextAvailability | false | |
| heal.identifier.secondary | http://thesis.ekt.gr/thesisBookReader/id/3654#page/1/mode/2up | |
| heal.language | el | |
| heal.numberOfPages | 169 σ. | |
| heal.publicationDate | 1995 | |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων Σχολή Ιατρικής Τμήμα Ιατρικής | el |
| heal.secondaryTitle | Ανοσολογικές διαταραχές | el |
| heal.type | doctoralThesis | |
| heal.type.el | Διδακτορική διατριβή | el |
| heal.type.en | Doctoral thesis | en |
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