Is androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?

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dc.contributor.authorPavlidis, N.en
dc.contributor.authorNikolaou, N.en
dc.contributor.authorTolis, C.en
dc.contributor.authorOrfanos, S.en
dc.contributor.authorTolis, G.en
dc.date.accessioned2015-11-24T19:08:56Z
dc.date.available2015-11-24T19:08:56Z
dc.identifier.issn0098-1532-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20622
dc.rightsDefault Licence-
dc.subjectAgeden
dc.subjectAntineoplastic Combined Chemotherapy Protocols/*adverse effects/therapeutic useen
dc.subjectBone Marrow/drug effectsen
dc.subjectBone Marrow Diseases/*chemically induced/drug therapyen
dc.subjectHodgkin Disease/complications/*drug therapyen
dc.subjectHumansen
dc.subjectHypogonadism/complications/*drug therapyen
dc.subjectMaleen
dc.subjectMechlorethamine/administration & dosage/adverse effectsen
dc.subjectPituitary Hormone-Releasing Hormones/deficiencyen
dc.subjectPrednisone/administration & dosage/adverse effectsen
dc.subjectProcarbazine/administration & dosage/adverse effectsen
dc.subjectTestosterone/*therapeutic useen
dc.subjectVincristine/administration & dosage/adverse effectsen
dc.titleIs androgen substitution necessary in hypogonadal patients when they are treated with chemotherapy for malignant diseases?en
heal.abstractA patient with hypogonadotropic hypogonadism owing to endogenous gonadotropin releasing hormone deficiency, who developed Hodgkin's disease is described. Chemotherapy administration caused prolonged and life-threatening myelosuppression; androgen substitution seemed to reverse bone marrow function and to maintain normal peripheral blood counts. Whether or not androgens are a necessary substitution in hypogonadal patients suffering from cancer and undergoing chemotherapy is discussed.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/2664441-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1002/mpo.2950170310/asset/2950170310_ftp.pdf?v=1&t=h0niod8i&s=37f7afb73cb548fe7873ba069ed4a7d3a86a6f5a-
heal.journalNameMed Pediatr Oncolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1989-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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