Short-term effects of atrial versus atrio-ventricular pacing on myocardial ischaemia in coronary artery disease patients
Φόρτωση...
Ημερομηνία
Συγγραφείς
Kyriakides, Z. S.
Kremastinos, D. T.
Kolettis, T. M.
Livanis, E.
Apostolou, T.
Michelakakis, N.
Toutouzas, P.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Eur Heart J
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
This investigation was undertaken to evaluate the effects of short-term atrial vs atrio-ventricular pacing on myocardial ischaemia. The study was in two parts. In part one, 12 coronary artery disease patients were studied to investigate the effects of the two pacing modes on angina pectoris, coronary sinus O2 saturation and lactate. The two pacing modes were each applied for 5 min at 25 beats.min-1 more than the maximum heart rate of the exercise test. Coronary sinus O2 saturation and lactate were estimated before and after pacing. In part two, 13 patients with left anterior descending coronary artery disease were studied to investigate the effects of the two pacing modes on coronary flow reserve, using a Doppler catheter in the above mentioned branch after the administration of 10 mg intracoronary papaverine. The pacing rate was 15 beats.min-1 greater than the resting heart rate. Coronary sinus lactate and O2 saturation changes were the same and angina pectoris developed at about the same time from the beginning of pacing under both modes. Coronary flow reserve was 2.1 +/- 0.7 during atrial pacing and 2.1 +/- 1.1 during atrio-ventricular pacing (ns). It is concluded that short-term atrial and atrio-ventricular pacing have the same effects on myocardial ischaemia in coronary artery disease patients.
Περιγραφή
Λέξεις-κλειδιά
Adult, Angina Pectoris/physiopathology/therapy, Blood Pressure/physiology, Bundle of His/physiopathology, Bundle-Branch Block/physiopathology/therapy, *Cardiac Pacing, Artificial, Coronary Circulation/physiology, Coronary Disease/physiopathology/*therapy, Female, Heart Atria/*physiopathology, Heart Catheterization, Heart Rate/physiology, Heart Ventricles/*physiopathology, Humans, Lactates/blood, Lactic Acid, Male, Middle Aged, Myocardial Ischemia/physiopathology/*therapy, Oxygen/blood
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/8508854
http://eurheartj.oxfordjournals.org/content/14/5/607
http://eurheartj.oxfordjournals.org/content/14/5/607
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής