Lipid parameters including Lp(a) in hemodialysis patients

dc.contributor.authorElisaf, M. S.en
dc.contributor.authorBairaktari, H.en
dc.contributor.authorTzallas, C.en
dc.contributor.authorGermanos, N.en
dc.contributor.authorKoulouridis, E.en
dc.contributor.authorPappas, M.en
dc.contributor.authorSiamopoulos, K. C.en
dc.contributor.authorTsolas, O.en
dc.date.accessioned2015-11-24T19:07:00Z
dc.date.available2015-11-24T19:07:00Z
dc.identifier.issn0886-022X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20395
dc.rightsDefault Licence-
dc.subjectArteriosclerosis/epidemiologyen
dc.subjectCoronary Disease/epidemiologyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectHyperlipidemias/epidemiologyen
dc.subjectIncidenceen
dc.subjectKidney Failure, Chronic/*blood/epidemiology/therapyen
dc.subjectLipids/*blooden
dc.subjectLipoprotein(a)/*blooden
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPrevalenceen
dc.subject*Renal Dialysisen
dc.subjectRisk Factorsen
dc.subjectTime Factorsen
dc.titleLipid parameters including Lp(a) in hemodialysis patientsen
heal.abstractChronic hemodialysis (CHD) patients have a high incidence and prevalence of atherosclerotic disease which may be related to numerous atherosclerotic risk factors. Among them dyslipidemia plays a significant role. Elevated Lp(a) levels, which are strongly associated with atherosclerosis, have been reported recently in uremic patients. The aim of our study was the determination of the levels of lipid parameters including Lp(a) in 151 CHD patients (76 male) aged 57 (12-81) years, who were on hemodialysis for a mean of 44.3 (range 1 to 189) months. Eighty-four normal individuals age and sex matched were used as controls. The median serum Lp(a) concentration in hemodialysis patients was 13 mg/dL compared with 6.5 mg/dL in healthy controls, p < 0.001 by distribution-free Mann-Whitney test. The prevalence of subjects with Lp(a) levels above 25 mg/dL was significantly higher in CHD patients compared to normal subjects (30% vs. 8%, p < 0.001). Even if CHD patients were matched for fasting lipid levels, they showed Lp(a) levels significantly higher than controls. No significant correlation was found between Lp(a) levels and either the age of the patients or the duration of hemodialysis. The etiology of primary renal disease did not influence the Lp(a) levels.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/7938758-
heal.identifier.secondaryhttp://informahealthcare.com/doi/abs/10.3109/08860229409045081-
heal.journalNameRen Failen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1994-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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