Labial minor salivary gland biopsy: a highly discriminatory diagnostic method between sarcoidosis and Sjogren's syndrome

dc.contributor.authorGiotaki, H.en
dc.contributor.authorConstantopoulos, S. H.en
dc.contributor.authorPapadimitriou, C. S.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T19:08:26Z
dc.date.available2015-11-24T19:08:26Z
dc.identifier.issn0025-7931-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20526
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBiopsyen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectLipen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectSalivary Glands/*pathologyen
dc.subjectSalivary Glands, Minor/*pathologyen
dc.subjectSarcoidosis/*pathologyen
dc.subjectSjogren's Syndrome/*pathologyen
dc.titleLabial minor salivary gland biopsy: a highly discriminatory diagnostic method between sarcoidosis and Sjogren's syndromeen
heal.abstractSixty labial minor salivary gland biopsies (lip biopsies) from 32 patients with sarcoidosis and 28 patients with primary Sjogren's syndrome were evaluated retrospectively and blindly. Six biopsies revealed typical sarcoid granulomata. All six belonged to patients with previously diagnosed sarcoidosis. Twelve lip biopsies, all from sarcoidosis patients, were classified as presenting 1+ or less lymphoid infiltrates according to Tarpley's classification. The biopsies of the remaining 14 patients with sarcoidosis showed normal tissues. Finally, 28 biopsies were classified as having 2+ or 3+ lymphoid infiltrates and/or fibrosis. All belonged to patients with Sjogren's syndrome. Our results indicate that lip biopsy has a rather low diagnostic yield in sarcoidosis (19%) but, more importantly, it can discriminate very well between sarcoidosis and Sjogren's syndrome.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/3749611-
heal.identifier.secondaryhttp://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000194916-
heal.journalNameRespirationen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1986-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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