Amount and composition of bone minerals in chronic liver disease

Απλή σελίδα τεκμηρίου
dc.contributor.authorKalef-Ezra, J. A.en
dc.contributor.authorMerkouropoulos, M. H.en
dc.contributor.authorChalla, A.en
dc.contributor.authorHatzikonstantinou, J.en
dc.contributor.authorKarantanas, A. H.en
dc.contributor.authorTsianos, E. V.en
dc.date.accessioned2015-11-24T19:36:44Z
dc.date.available2015-11-24T19:36:44Z
dc.identifier.issn0163-2116-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23932
dc.rightsDefault Licence-
dc.subjectAbsorptiometry, Photon/statistics & numerical dataen
dc.subjectAdulten
dc.subjectAgeden
dc.subjectBiological Markers/blooden
dc.subjectBone and Bones/*chemistry/radiographyen
dc.subjectChronic Diseaseen
dc.subjectFemaleen
dc.subjectHepatitis B/*metabolism/radiographyen
dc.subjectHepatitis C/*metabolism/radiographyen
dc.subjectHepatitis D/*metabolism/radiographyen
dc.subjectHepatitis, Chronic/*metabolism/radiographyen
dc.subjectHumansen
dc.subjectLinear Modelsen
dc.subjectLiver Cirrhosis/*metabolism/radiographyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMinerals/*analysisen
dc.subjectNeutron Activation Analysis/statistics & numerical dataen
dc.titleAmount and composition of bone minerals in chronic liver diseaseen
heal.abstractAlterations in bone mineral are a common complication of chronic liver disease. The aim of the current study was to assess bone mineral status in patients with chronic liver disease not treated with corticosteroids and to investigate any possible correlation with the histological stage of liver disease. Bone mineral status in 27 patient with chronic active hepatitis, and 17 with active cirrhosis was compared to that of matched controls. Partial body neutron activation analysis was applied for measuring hand bone phosphorus, single-photon absorptiometry for measuring forearm bone mineral content, and dual-energy x-ray absorptiometry for measuring spinal bone mineral density. These noninvasive measurements were supplemented with data obtained by high resolution radiography and biochemistry. Decreased metacarpal cortical thickness was found in five patients, all in the cirrhotic group. In addition, both mean intact parathyroid hormone and 25-hydroxyvitamin D levels were reduced in this group of patients. The mean values of the quantities assessed by the in vivo techniques in patients in the early stages of the hepatic disease did not differ statistically from those of matched normal controls. On the contrary, these quantities were reduced by 9% in the patients at the late stages relative to controls. In conclusion, only the late stages of liver disease are associated with an increased risk of fractures.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/8625743-
heal.identifier.secondaryhttp://www.springerlink.com/content/r4nx4222080584x2/fulltext.pdf-
heal.journalNameDig Dis Scien
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1996-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

Αρχεία

Φάκελος/Πακέτο αδειών

Προβολή: 1 - 1 of 1
Μικρογραφία εικόνας
Ονομα:
license.txt
Μέγεθος:
1.74 KB
Μορφότυπο:
Item-specific license agreed upon to submission
Περιγραφή:
Κατεβάστε

Συλλογές

Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ