The unmet treatment need for moderate to severe psoriasis: results of a survey and chart review
Φόρτωση...
Ημερομηνία
Συγγραφείς
Christophers, E.
Griffiths, C. E.
Gaitanis, G.
van de Kerkhof, P.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
J Eur Acad Dermatol Venereol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
BACKGROUND: Conventional systemic therapies and phototherapy for psoriasis are limited by safety concerns that may preclude long-term treatment with these agents. OBJECTIVES: To estimate the unmet need for safe and effective treatments for psoriasis. METHODS: A survey was conducted at three psoriasis outpatient clinics in Europe. Male and female patients of any age with psoriasis requiring more than topical treatment were eligible to participate in the survey. Patient data were obtained from patients' answers to a questionnaire as well as by a chart review of each participating patient. The survey questionnaire addressed various aspects of psoriasis, including demographics and disease characteristics, treatment history, pre-existing medical conditions, and patient satisfaction with treatments received. RESULTS: A total of 301 patients participated in the survey, with approximately 100 patients from each centre. Nearly 90% of patients had received at least one systemic therapy or phototherapy for psoriasis, with 39% of patients receiving three or more. Ultraviolet B (UVB), methotrexate, psoralen plus ultraviolet A (PUVA), retinoids and cyclosporin were the most commonly used agents. Inadequate response, reported by patients as no change or worsening of disease with treatment, ranged from 10% to 50%. Contraindications to conventional systemic therapies were reported by 9-22% of patients. A substantial number of patients (42%) were not satisfied with these therapies. CONCLUSIONS: This survey highlights the unmet need for safe and effective therapies for moderate to severe psoriasis.
Περιγραφή
Λέξεις-κλειδιά
Adult, Data Collection, Female, Ficusin/therapeutic use, Humans, Male, Methotrexate/therapeutic use, Middle Aged, Patient Satisfaction, Photochemotherapy, Psoriasis/*drug therapy
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/16922938
http://onlinelibrary.wiley.com/store/10.1111/j.1468-3083.2006.01667.x/asset/j.1468-3083.2006.01667.x.pdf?v=1&t=h0t9yy6n&s=15c2b77c4d53ef3e993dc7ca3e28aab1ebfa498c
http://onlinelibrary.wiley.com/store/10.1111/j.1468-3083.2006.01667.x/asset/j.1468-3083.2006.01667.x.pdf?v=1&t=h0t9yy6n&s=15c2b77c4d53ef3e993dc7ca3e28aab1ebfa498c
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής