Association of Metsovo lung and pleural mesothelioma with exposure to tremolite-containing whitewash

dc.contributor.authorLanger, A. M.en
dc.contributor.authorNolan, R. P.en
dc.contributor.authorConstantopoulos, S. H.en
dc.contributor.authorMoutsopoulos, H. M.en
dc.date.accessioned2015-11-24T19:34:46Z
dc.date.available2015-11-24T19:34:46Z
dc.identifier.issn0140-6736-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23650
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subject*Asbestos, Amphiboleen
dc.subjectCalcinosis/epidemiology/*etiologyen
dc.subjectEnvironmental Exposureen
dc.subjectFemaleen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectLung Diseases/epidemiology/*etiologyen
dc.subjectMaleen
dc.subjectMesothelioma/epidemiology/*etiologyen
dc.subjectMiddle Ageden
dc.subjectPaint/analysisen
dc.subjectPleural Neoplasms/epidemiology/*etiologyen
dc.subjectSilicic Acid/*adverse effects/analysisen
dc.subjectSilicon Dioxide/*adverse effectsen
dc.subjectX-Ray Diffractionen
dc.titleAssociation of Metsovo lung and pleural mesothelioma with exposure to tremolite-containing whitewashen
heal.abstractPleural thickening, bilateral pleural hyalinised plaques, and restrictive lung function are found among inhabitants of four small villages in northwestern Greece. Transbronchial biopsy samples from patients with disease contained tremolite fibres. Malignant pleural mesothelioma has now been reported in these villages and accounts for approximately 1% of the total mortality from 1981 to 1985. The principal whitewash once used in this area is predominantly asbestiform tremolite. The fibre is identical in every respect to fibres found in the lung tissues of people with Metsovo lung. The membrane activity of this tremolite is greater than that of the commercially used asbestiform amphiboles amosite and crocidolite. This measure of cytotoxicity lends further support to the hypothesis that this fibre is the agent of Metsovo lung and mesothelioma.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/2882352-
heal.journalNameLanceten
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1987-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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