Duloxetine-induced hypomania: case report and brief review of the literature on SNRIs-induced mood switching

dc.contributor.authorPeritogiannis, V.en
dc.contributor.authorAntoniou, K.en
dc.contributor.authorMouka, V.en
dc.contributor.authorMavreas, V.en
dc.contributor.authorHyphantis, T. N.en
dc.date.accessioned2015-11-24T19:23:31Z
dc.date.available2015-11-24T19:23:31Z
dc.identifier.issn0269-8811-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/22324
dc.rightsDefault Licence-
dc.subjectBipolar Disorder/*chemically induceden
dc.subjectDepressive Disorder/drug therapyen
dc.subjectDose-Response Relationship, Drugen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMiddle Ageden
dc.subjectSerotonin Uptake Inhibitors/administration & dosage/*adverse effects/therapeuticen
dc.subjectuseen
dc.subjectThiophenes/administration & dosage/*adverse effects/therapeutic useen
dc.titleDuloxetine-induced hypomania: case report and brief review of the literature on SNRIs-induced mood switchingen
heal.abstractManic switching during antidepressant treatment has been reported with every class of antidepressant drugs. Serotonin-noradrenaline reuptake inhibitors (SNRIs) have been increasingly used for the treatment of unipolar and bipolar depression and are well tolerated and sufficiently effective because of their dual mechanism of action. A case of duloxetine-induced hypomania in a non-bipolar patient is presented, and a brief review of all cases of SNRIs' induced mania and hypomania has been carried out. The available data suggest that SNRIs, especially venlafaxine, can induce mood switching in patients with bipolar depression and in certain patients with unipolar depression, but the potential of duloxetine and milnacipran to induce manic or hypomanic symptoms cannot be disregarded. Switching appears to be dose-related and treatment initiation with lower doses and upward titration when needed may be preferable in selected cases and may help minimizing the risk of mood switching.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1177/0269881108089841-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18562441-
heal.identifier.secondaryhttp://jop.sagepub.com/content/23/5/592.full.pdf-
heal.journalNameJ Psychopharmacolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2009-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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