Clinical and angiographic follow-up after overlapping implantation of polytetrafluoroethylene covered stents with drug eluting stents

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dc.contributor.authorPapafaklis, M. I.en
dc.contributor.authorSianos, G.en
dc.contributor.authorCost, B.en
dc.contributor.authorVaina, S.en
dc.contributor.authorManginas, A.en
dc.contributor.authorDardas, P. S.en
dc.contributor.authorTsikaderis, D.en
dc.contributor.authorvan Mieghem, C. A.en
dc.contributor.authorMichalis, L. K.en
dc.contributor.authorSerruys, P. W.en
dc.date.accessioned2015-11-24T19:30:25Z
dc.date.available2015-11-24T19:30:25Z
dc.identifier.issn1774-024X-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23090
dc.rightsDefault Licence-
dc.titleClinical and angiographic follow-up after overlapping implantation of polytetrafluoroethylene covered stents with drug eluting stentsen
heal.abstractPolytetrafluoroethylene-covered stents (PCS) were recently proposed as a new modality mainly for the treatment of saphenous vein graft lesions, but restenosis occurring principally at the edges restricted their clinical use in the management of coronary aneurysms and perforations.Aims: To investigate the safety and effectiveness of the overlapping implantation of drug-eluting stents (DES) with PCS in clinical scenarios where the latter are indicated.Methods: Since April 2002, when DES were introduced in clinical practice, 14 consecutive patients were -treated with overlapping implantation of PCS with DES in 3 centres. Seven patients were treated for coronary aneurysms, 5 for coronary perforations and 2 for branch occlusion. The incidence of any major adverse cardiac events defined as death, myocardial infarction (MI), and target vessel revascularisation (TVR) was retrospectively evaluated. A control angiography was available in 13 patients, and quantitative coronary angiography was performed before and after the intervention and at follow-up to evaluate restenosis rate and late loss.Results: At a mean clinical follow-up of 21.9 months there were no deaths or MI's, while one patient with occlusive restenosis underwent successful TVR (7.7%). At angiographic follow-up (mean: 9.7 months) there was one patient with restenosis (7.7%), who had a total occlusion. After excluding the patient with the occlusive restenosis mean diameter stenosis was 22.4+/-11.7% and late loss was 0.18+/-0.35 mm at follow-up. No early or late stent thrombosis occurred.Conclusion: Overlapping implantation of PCS with DES seems to be a safe and effective therapeutic modality demonstrating a low incidence of clinical and angiographic restenosis.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/19755264-
heal.journalNameEuroInterventionen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2006-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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