Malignancies in beta-thalassemia patients: a single-center experience and a concise review of the literature
dc.contributor.author | Benetatos, L. | en |
dc.contributor.author | Alymara, V. | en |
dc.contributor.author | Vassou, A. | en |
dc.contributor.author | Bourantas, K. L. | en |
dc.date.accessioned | 2015-11-24T19:05:41Z | |
dc.date.available | 2015-11-24T19:05:41Z | |
dc.identifier.issn | 1751-5521 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20225 | |
dc.rights | Default Licence | - |
dc.subject | Adult | en |
dc.subject | Female | en |
dc.subject | Hodgkin Disease/complications/diagnosis/therapy | en |
dc.subject | Humans | en |
dc.subject | Lymphoma, Non-Hodgkin/complications/diagnosis/drug therapy | en |
dc.subject | Male | en |
dc.subject | Middle Aged | en |
dc.subject | Neoplasms/*complications | en |
dc.subject | Radiotherapy, Adjuvant | en |
dc.subject | Seminoma/complications/diagnosis/therapy | en |
dc.subject | Testicular Neoplasms/complications/diagnosis/therapy | en |
dc.subject | beta-Thalassemia/*complications/diagnosis/*physiopathology/therapy | en |
dc.title | Malignancies in beta-thalassemia patients: a single-center experience and a concise review of the literature | en |
heal.abstract | Thalassemia represents the world's most common monogenic disease, characterized by absence of or decreased globin chain production. The lifespan of thalassemia patients has been extended as a result of current supportive treatment. We report three cases of cancer (non-Hodgkin lymphoma, Hodgkin disease, and seminoma) in thalassemic patients. Factors that may contribute to the pathogenesis of cancer seem to be infections and iron overload through mechanisms of oxidative damage; immunomodulation or coexistence of the two diseases may only be coincidental. | en |
heal.access | campus | - |
heal.fullTextAvailability | TRUE | - |
heal.identifier.primary | 10.1111/j.1751-553X.2007.00929.x | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18333849 | - |
heal.identifier.secondary | http://onlinelibrary.wiley.com/store/10.1111/j.1751-553X.2007.00929.x/asset/j.1751-553X.2007.00929.x.pdf?v=1&t=h2bog6dh&s=7eecd77d7c2dadb346c9d1c1f846199171014071 | - |
heal.journalName | Int J Lab Hematol | en |
heal.journalType | peer-reviewed | - |
heal.language | en | - |
heal.publicationDate | 2008 | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.type | journalArticle | - |
heal.type.el | Άρθρο Περιοδικού | el |
heal.type.en | Journal article | en |
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