Malignancies in beta-thalassemia patients: a single-center experience and a concise review of the literature

dc.contributor.authorBenetatos, L.en
dc.contributor.authorAlymara, V.en
dc.contributor.authorVassou, A.en
dc.contributor.authorBourantas, K. L.en
dc.date.accessioned2015-11-24T19:05:41Z
dc.date.available2015-11-24T19:05:41Z
dc.identifier.issn1751-5521-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20225
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectFemaleen
dc.subjectHodgkin Disease/complications/diagnosis/therapyen
dc.subjectHumansen
dc.subjectLymphoma, Non-Hodgkin/complications/diagnosis/drug therapyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectNeoplasms/*complicationsen
dc.subjectRadiotherapy, Adjuvanten
dc.subjectSeminoma/complications/diagnosis/therapyen
dc.subjectTesticular Neoplasms/complications/diagnosis/therapyen
dc.subjectbeta-Thalassemia/*complications/diagnosis/*physiopathology/therapyen
dc.titleMalignancies in beta-thalassemia patients: a single-center experience and a concise review of the literatureen
heal.abstractThalassemia represents the world's most common monogenic disease, characterized by absence of or decreased globin chain production. The lifespan of thalassemia patients has been extended as a result of current supportive treatment. We report three cases of cancer (non-Hodgkin lymphoma, Hodgkin disease, and seminoma) in thalassemic patients. Factors that may contribute to the pathogenesis of cancer seem to be infections and iron overload through mechanisms of oxidative damage; immunomodulation or coexistence of the two diseases may only be coincidental.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1111/j.1751-553X.2007.00929.x-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18333849-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1751-553X.2007.00929.x/asset/j.1751-553X.2007.00929.x.pdf?v=1&t=h2bog6dh&s=7eecd77d7c2dadb346c9d1c1f846199171014071-
heal.journalNameInt J Lab Hematolen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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