Results of treatment of cystinuria and cystine lithiasis with alpha-mercaptopropionylglycine. Apropos of 40 patients

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dc.contributor.authorGiannakopoulos, X.en
dc.contributor.authorKalfakakou, V.en
dc.contributor.authorTsoumanis, P.en
dc.contributor.authorKarkabounas, S.en
dc.contributor.authorGiannakis, D.en
dc.contributor.authorChambilomatis, P.en
dc.contributor.authorEvangelou, A.en
dc.contributor.authorKallistratos, G.en
dc.date.accessioned2015-11-24T18:53:46Z
dc.date.available2015-11-24T18:53:46Z
dc.identifier.issn0248-0018-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18605
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectCystine/analysisen
dc.subjectCystinuria/complications/drug therapyen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectRecurrenceen
dc.subjectTiopronin/administration & dosage/therapeutic useen
dc.subjectUrinary Calculi/chemistry/complications/drug therapy/radiographyen
dc.subjectUrographyen
dc.titleResults of treatment of cystinuria and cystine lithiasis with alpha-mercaptopropionylglycine. Apropos of 40 patientsen
heal.abstractFrom 1987 to 1990, 719 subjects (385 males and 334 females) were screened, by means of urocystin-kit, for cystinuria and cystine lithiasis, in Epirus district (North-West Greece). The positive results were confirmed by chromatographic analysis of urine amino acids and laboratory tests. Forty patients, belonging to six cystinuric families, were identified. These patients were excreting 3.1 +/- 1.7 mmol/24 h of cystine in urine. All patients were treated by per os administration of alpha-MPG in daily doses of 400-1,200 mg/24 h). We therefore report the results of a 4 +/- 2 year follow-up of these patients. We conclude that treatment with alpha-MPG is very effective with minimal side effects in patients suffering from cystinuria or cystine urinary calculi.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/7836789-
heal.journalNameJ Urol (Paris)en
heal.journalTypepeer-reviewed-
heal.languagefr-
heal.publicationDate1994-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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