Large loop excision of the transformation zone for treating cervical intraepithelial neoplasia: a 12-year experience

Απλή σελίδα τεκμηρίου
dc.contributor.authorParaskevaidis, E.en
dc.contributor.authorKoliopoulos, G.en
dc.contributor.authorMalamou-Mitsi, V.en
dc.contributor.authorZikopoulos, K.en
dc.contributor.authorPaschopoulos, M.en
dc.contributor.authorPappa, L.en
dc.contributor.authorAgnantis, N. J.en
dc.contributor.authorLoli, D. E.en
dc.date.accessioned2015-11-24T19:08:00Z
dc.date.available2015-11-24T19:08:00Z
dc.identifier.issn0250-7005-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/20486
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectCarcinoma, Squamous Cell/pathology/*surgeryen
dc.subjectCervical Intraepithelial Neoplasia/pathology/*surgeryen
dc.subjectColposcopyen
dc.subjectConizationen
dc.subjectElectrocoagulationen
dc.subjectFemaleen
dc.subjectFollow-Up Studiesen
dc.subjectGynecologic Surgical Procedures/*methodsen
dc.subjectHumansen
dc.subjectNeoplasm Invasivenessen
dc.subjectPregnancyen
dc.subjectPregnancy Complications, Neoplasticen
dc.subjectRetrospective Studiesen
dc.subjectTreatment Outcomeen
dc.subjectUterine Cervical Neoplasms/pathology/*surgeryen
dc.titleLarge loop excision of the transformation zone for treating cervical intraepithelial neoplasia: a 12-year experienceen
heal.abstractBACKGROUND: Although the existing evidence suggests that there is no obviously superior conservative method for treating cervical intraepithelial neoplasia (CIN), one of the most widely used is the large loop excision of the transformation zone (LLETZ). MATERIALS AND METHODS: A total of 897 women who were treated with LLETZ at our colposcopy clinic from 1989 to 2000 were retrospectively studied. RESULTS: Forty women did not have significant cervical pathology (4.5% over-treatment rate). Clear margins of excision were obtained in 748 (88.5%) of the 845 cases of CIN or microinvasive cancers. Treatment failure rates were 4.7% for clear margins and 26.8% for involved or uncertain. CONCLUSION: LLETZ is a fast and reliable method of treating CIN and microinvasive carcinoma. Generalized cauterization of the resulting crater should be avoided and satellite HPV lesions ablated. Involved margins have a higher treatmentfailure rate, therefore a larger excision is recommended as cervical craters regenerate. Treatment in pregnant women can be delayed until postpartum provided they have adequate surveillance during pregnancy.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/11712817-
heal.journalNameAnticancer Researchen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2001-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

Αρχεία

Φάκελος/Πακέτο αδειών

Προβολή: 1 - 1 of 1
Μικρογραφία εικόνας
Ονομα:
license.txt
Μέγεθος:
1.74 KB
Μορφότυπο:
Item-specific license agreed upon to submission
Περιγραφή:
Κατεβάστε

Συλλογές

Άρθρα σε επιστημονικά περιοδικά ( Ανοικτά) - ΙΑΤ