A simple procedure for estimation of total body surface area and determination of a new value of Meeh's constant in rats
| dc.contributor.author | Gouma, E. | en |
| dc.contributor.author | Simos, Y. | en |
| dc.contributor.author | Verginadis, I. | en |
| dc.contributor.author | Lykoudis, E. | en |
| dc.contributor.author | Evangelou, A. | en |
| dc.contributor.author | Karkabounas, S. | en |
| dc.date.accessioned | 2015-11-24T19:39:06Z | |
| dc.date.available | 2015-11-24T19:39:06Z | |
| dc.identifier.issn | 1758-1117 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24213 | |
| dc.rights | Default Licence | - |
| dc.title | A simple procedure for estimation of total body surface area and determination of a new value of Meeh's constant in rats | en |
| heal.abstract | Precise calculation of total body surface area (TBSA) or premarked surface areas (P-MSAs) is of great importance in many biomedical applications. The aim of the paper was to present a simple procedure of measurement of P-MSAs in small animals and to determine a more accurate Meeh's constant (k), for a commonly used weight range of laboratory rats. A series of 30 Wistar rats, weighing 195-240 g, were anaesthetized and weighted. The TBSA of each animal was measured using a clear pocket and a planimeter. The data obtained were entered into the Meeh's formula (TBSA = kW(2/3)), the most commonly used for small experimental animals, so that a k value for each animal as well as a mean k value (9.83) were obtained. The TBSA of the animals was also calculated using the aforementioned mean k value and compared with that obtained using k values reported in previous studies. According to our findings, the new mean k value, determined with the use of our procedure of surface area measurement, ensured greater accuracy in the determination of the TBSA of experimental rats of a specific weight range. We also suggest a new procedure of surface area measurement which is easy, accurate and does not require animal sacrifice. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1258/la.2011.011021 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/22008848 | - |
| heal.identifier.secondary | http://la.rsmjournals.com/content/46/1/40.full.pdf | - |
| heal.journalName | Lab Anim | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2012 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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