Computerized analysis of digital subtraction angiography: a tool for quantitative in-vivo vascular imaging
Φόρτωση...
Ημερομηνία
Συγγραφείς
Kagadis, G. C.
Spyridonos, P.
Karnabatidis, D.
Diamantopoulos, A.
Athanasiadis, E.
Daskalakis, A.
Katsanos, K.
Cavouras, D.
Mihailidis, D.
Siablis, D.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
J Digit Imaging
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
The purpose of our study was to develop a user-independent computerized tool for the automated segmentation and quantitative assessment of in vivo-acquired digital subtraction angiography (DSA) images. Vessel enhancement was accomplished based on the concept of image structural tensor. The developed software was tested on a series of DSA images acquired from one animal and two human angiogenesis models. Its performance was evaluated against manually segmented images. A receiver's operating characteristic curve was obtained for every image with regard to the different percentages of the image histogram. The area under the mean curve was 0.89 for the experimental angiogenesis model and 0.76 and 0.86 for the two clinical angiogenesis models. The coordinates of the operating point were 8.3% false positive rate and 92.8% true positive rate for the experimental model. Correspondingly for clinical angiogenesis models, the coordinates were 8.6% false positive rate and 89.2% true positive rate and 9.8% false positive rate and 93.8% true positive rate, respectively. A new user-friendly tool for the analysis of vascular networks in DSA images was developed that can be easily used in either experimental or clinical studies. Its main characteristics are robustness and fast and automatic execution.
Περιγραφή
Λέξεις-κλειδιά
Angiography, Digital Subtraction/*methods, Animals, Contrast Media/diagnostic use, Disease Models, Animal, False Negative Reactions, False Positive Reactions, Hindlimb/blood supply/radiography, Humans, Image Processing, Computer-Assisted/*methods, Neovascularization, Pathologic/radiography, Normal Distribution, Observer Variation, ROC Curve, Rabbits, Radiographic Image Enhancement/methods, Reproducibility of Results, Sensitivity and Specificity, Software, Subclavian Artery/radiography, Triiodobenzoic Acids/diagnostic use
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/17674102
http://www.springerlink.com/content/4m78w26860g17935/fulltext.pdf
http://www.springerlink.com/content/4m78w26860g17935/fulltext.pdf
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής