The outcome of infants younger than 6 months requiring ventilation for pneumonia caused by Mycobacterium tuberculosis
Φόρτωση...
Ημερομηνία
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Pediatr Pulmonol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
INTRODUCTION: The outcome of young infants (<6 months) being ventilated for respiratory failure caused by Mycobacterium tuberculosis (MTB) has not been recorded. PATIENTS AND METHODS: A descriptive study of children <6 months admitted to the PICU from 1 February 1999 to 31 December 2005 with MTB causing respiratory failure. RESULTS: Seventeen infants were ventilated for respiratory failure caused by MTB: ten had ventilatory respiratory failure and seven had hypoxic failure. An index case was found in 47%. All chest radiographs (CXRs) were highly suggestive of tuberculosis. MTB was cultured in 15 cases. In the other two cases MTB was confirmed by histopathology. The median duration of ventilation was 6 days (range: 1-35 days) with a median PaO2/FiO2 of 85 and ventilatory index of 58. Transthoracic glandular enucleation was required to facilitate extubation in six babies. All the infants survived. At 6-month follow-up 35% had a normal CXR and all were asymptomatic. One child had CXR changes suggestive of bronchiectasis but was asymptomatic. CONCLUSION: The outcome of infants <6 months ventilated for respiratory failure caused by MTB is very good if TB is recognized timeously and appropriate management started. The diagnosis of TB in these infants can be made with a high index of suspicion and careful evaluation of the CXR.
Περιγραφή
Λέξεις-κλειδιά
Bronchiectasis/etiology/radiography, Bronchoscopy, Female, Follow-Up Studies, Humans, Infant, Length of Stay, Lung/radiography/surgery, Male, Mycobacterium tuberculosis/*isolation & purification, Pneumonia/complications/*microbiology/*therapy, Respiration, Artificial/*methods, Respiratory Insufficiency/microbiology/therapy, Tomography, X-Ray Computed, Treatment Outcome, Tuberculosis/*complications/diagnosis/drug therapy
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/18383116
http://onlinelibrary.wiley.com/store/10.1002/ppul.20812/asset/20812_ftp.pdf?v=1&t=h0cb0s3y&s=3104f9891472eedb7f1d15faa2b68d392b5aadf1
http://onlinelibrary.wiley.com/store/10.1002/ppul.20812/asset/20812_ftp.pdf?v=1&t=h0cb0s3y&s=3104f9891472eedb7f1d15faa2b68d392b5aadf1
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής
