Primary Sjogren syndrome in the paediatric age: a multicentre survey

dc.contributor.authorCimaz, R.en
dc.contributor.authorCasadei, A.en
dc.contributor.authorRose, C.en
dc.contributor.authorBartunkova, J.en
dc.contributor.authorSediva, A.en
dc.contributor.authorFalcini, F.en
dc.contributor.authorPicco, P.en
dc.contributor.authorTaglietti, M.en
dc.contributor.authorZulian, F.en
dc.contributor.authorTen Cate, R.en
dc.contributor.authorSztajnbok, F. R.en
dc.contributor.authorVoulgari, P. V.en
dc.contributor.authorDrosos, A. A.en
dc.date.accessioned2015-11-24T18:56:28Z
dc.date.available2015-11-24T18:56:28Z
dc.identifier.issn0340-6199-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19045
dc.rightsDefault Licence-
dc.subjectChilden
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectParotid Diseases/etiologyen
dc.subjectSjogren's Syndrome/diagnosis/*epidemiology/therapyen
dc.titlePrimary Sjogren syndrome in the paediatric age: a multicentre surveyen
heal.abstractPrimary Sjogren syndrome (SS) is very rare in childhood. We collected a series of primary paediatric SS cases from different centres. A data collection form was prepared and sent to rheumatologists who were willing to participate. Data on 40 cases of primary SS with onset before the 16th birthday were collected. Almost all patients (35/40) were females, age at onset varied from 9.3 to 12.4 years (mean 10.7 years). Signs and symptoms at disease onset were mainly recurrent parotid swelling followed by sicca symptoms. Abnormal laboratory tests were found in the majority of cases. Regarding treatment, 22 patients were treated at some time with oral corticosteroids, seven with non-steroidal anti-inflammatory drugs, and five with hydroxychloroquine; two patients needed cyclosporine and one cyclophosphamide. Follow-up varied from 0 to 7.5 years from onset, without major complications in the majority of patients. CONCLUSION: recurrent parotid swelling is a common feature of primary Sjogren syndrome in childhood and often occurs as a presenting feature. Sicca symptoms may be rarer.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1007/s00431-003-1277-9-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/12898241-
heal.identifier.secondaryhttp://www.springerlink.com/content/la97ytpvjdf52jh5/fulltext.pdf-
heal.journalNameEur J Pediatren
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2003-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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