Metabolic abnormalities in patients with primary open-angle glaucoma
| dc.contributor.author | Elisaf, M. S. | en |
| dc.contributor.author | Kitsos, G. | en |
| dc.contributor.author | Bairaktari, E. | en |
| dc.contributor.author | Kalaitzidis, R. | en |
| dc.contributor.author | Kalogeropoulos, C. | en |
| dc.contributor.author | Psilas, K. | en |
| dc.date.accessioned | 2015-11-24T19:04:39Z | |
| dc.date.available | 2015-11-24T19:04:39Z | |
| dc.identifier.issn | 1395-3907 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20082 | |
| dc.rights | Default Licence | - |
| dc.subject | Aged | en |
| dc.subject | Blood Glucose/analysis | en |
| dc.subject | Carbohydrate Metabolism | en |
| dc.subject | Diabetes Complications | en |
| dc.subject | Female | en |
| dc.subject | Glaucoma, Open-Angle/blood/*complications/etiology | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Metabolic Diseases/blood/*complications | en |
| dc.subject | Middle Aged | en |
| dc.subject | Risk Factors | en |
| dc.subject | Uric Acid/blood | en |
| dc.title | Metabolic abnormalities in patients with primary open-angle glaucoma | en |
| heal.abstract | PURPOSE: Although there are few data on the underlying mechanisms of primary open-angle glaucoma (POAG), it has been suggested that metabolic diseases may play a role in the evolution of the disease. We carried out the present study to investigate the involvement of metabolic disturbances in POAG pathogenesis. MATERIAL/METHODS: Serum metabolic parameters were evaluated in 49 POAG patients without a known history of diabetes mellitus and 72 age and sex matched individuals without glaucoma (control group). RESULTS: Among the metabolic parameters examined, only fasting serum glucose and uric acid levels were found significantly higher in patients with glaucoma compared to the control population (117+/-17 mg/dl vs 105+/-11 mg/dl, p=0.05 and 6.2+/-1.9 mg/dl vs 5+/-1.2 mg/dl, p=0.006, respectively). Additionally, a considerably greater proportion of patients had disturbances of the carbohydrate metabolism and hyperuricemia. CONCLUSION: We conclude that disturbances of carbohydrate and uric acid metabolism could play a role in glaucoma damage and pathogenesis. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/11284749 | - |
| heal.journalName | Acta Ophthalmol Scand | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2001 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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