Neurological manifestations of connective tissue diseases mimicking multiple sclerosis
Φόρτωση...
Ημερομηνία
Συγγραφείς
Pelidou, S. H.
Giannopoulos, S.
Tzavidi, S.
Tsifetaki, N.
Kitsos, G.
Stefanou, D.
Kostadima, V.
Drosos, A. A.
Kyritsis, A. P.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Rheumatol Int
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
The objective of the study was to analyze retrospectively the clinical, laboratory and imaging findings of multiple sclerosis (MS), such as the manifestations in a cohort of 132 patients referred to the neurology in and outpatient clinic. The proposed clinical and laboratory diagnostic criteria for MS and connective tissue disorders were systematically assessed in 132 consecutive patients. Cerebrospinal fluid serology and brain or spinal cord MRI were studied in all cases. In patients suspected for connective tissue disorder, schirmer test, rose bengal staining and biopsy of minor salivary glands were performed. A total of 115 (87%) patients were diagnosed to have definite MS, while 17 (13%) were diagnosed to have connective tissue disorder. Positive neurological and MRI findings were observed in both groups. The majority of patients with connective tissue disorder demonstrated extra-neurological manifestations like Raynaud's phenomenon, arthritis, livedo reticularis, purpura and presence of multiple autoantibodies in their sera. All patients with MS should be screened systematically for connective tissue disorder. In the absence of pathognomonic clinical and laboratory findings, the diagnosis of MS is a diagnosis of exclusion.
Περιγραφή
Λέξεις-κλειδιά
multiple sclerosis, connective tissue disease, Sjogren syndrome, systemic lupus erythematosus, APS, systemic-lupus-erythematosus, central-nervous-system, primary, sjogrens-syndrome, antiphospholipid syndrome, classification criteria, cerebrospinal-fluid, diagnosis, prevalence, alpha
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
<Go to ISI>://WOS:000249803400003
http://link.springer.com/content/pdf/10.1007%2Fs00296-007-0384-8.pdf
http://link.springer.com/content/pdf/10.1007%2Fs00296-007-0384-8.pdf
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής