Antibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intolerance

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dc.contributor.authorMoutsopoulos, H. M.en
dc.contributor.authorGiotaki, H.en
dc.contributor.authorMaddison, P. J.en
dc.contributor.authorMavridis, A. C.en
dc.contributor.authorDrosos, A. A.en
dc.contributor.authorSkopouli, F. N.en
dc.date.accessioned2015-11-24T19:36:07Z
dc.date.available2015-11-24T19:36:07Z
dc.identifier.issn0003-4967-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23810
dc.rightsDefault Licence-
dc.subjectAdulten
dc.subjectAgeden
dc.subjectAntigens/*immunologyen
dc.subjectArthritis, Rheumatoid/drug therapy/immunologyen
dc.subjectAutoantibodies/*analysisen
dc.subject*Autoantigensen
dc.subjectAutoimmune Diseases/*immunologyen
dc.subjectFemaleen
dc.subjectGreeceen
dc.subjectHumansen
dc.subjectLupus Erythematosus, Systemic/immunologyen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectPenicillamine/adverse effectsen
dc.subject*RNA, Small Cytoplasmicen
dc.subjectRheumatic Diseases/*immunologyen
dc.subject*Ribonucleoproteinsen
dc.subjectScleroderma, Systemic/immunologyen
dc.subjectSjogren's Syndrome/immunologyen
dc.titleAntibodies to cellular antigens in Greek patients with autoimmune rheumatic diseases: anti-Ro(SSA) antibody a possible marker of penicillamine-D intoleranceen
heal.abstractOne hundred and twenty-four sera from Greek patients with autoimmune rheumatic diseases (29 with systemic lupus erythematosus (SLE), 24 with scleroderma, 11 with primary Sjogren's syndrome (SS), and 60 with rheumatoid arthritis (RA) were tested for antibodies to nRNP, Sm, Scl-70, Ro(SSA), and La(SSB) cellular antigens. The incidence of these antibodies in the different groups of patients examined, did not differ overall from that described previously. It was noted, however, that antibodies to Sm were very infrequently found in Greek patients with SLE and anti-Ro positive patients with SLE did not have the clinical manifestations described by other workers. Finally, it was found that anti-Ro positive patients with RA experienced a high frequency of side effects from penicillamine-D. The significance of these findings is discussed.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/6608925-
heal.identifier.secondaryhttp://ard.bmj.com/content/43/2/285.full.pdf-
heal.journalNameAnn Rheum Disen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1984-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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