Six Mantoux tuberculin skin tests with 1, 2, 5, 10, 20, and 50 units in a healthy male without side-effects - is skin reaction a linear function of tuberculin dose?
| dc.contributor.author | Dimoliatis, I. D. | en |
| dc.contributor.author | Liaskos, C. A. | en |
| dc.date.accessioned | 2015-11-24T18:51:23Z | |
| dc.date.available | 2015-11-24T18:51:23Z | |
| dc.identifier.issn | 1757-1626 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/18252 | |
| dc.rights | Default Licence | - |
| dc.title | Six Mantoux tuberculin skin tests with 1, 2, 5, 10, 20, and 50 units in a healthy male without side-effects - is skin reaction a linear function of tuberculin dose? | en |
| heal.abstract | ABSTRACT: BACKGROUND: Tuberculosis remains a serious disease worldwide. Anti-tuberculosis campaigners many times face negative tuberculin skin tests after Bacille Calmette Guerin vaccination. Increasing tuberculin units might be a solution. However, is skin reaction a linear function of tuberculin dose? Are there any side-effects when higher tuberculin doses are administered? CASE PRESENTATION: Six simultaneous Mantoux tuberculin skin tests, using 1, 2, 5, 10, 20, and 50 tuberculin units (88 altogether) of purified protein derivative RT23 per 0.1 mL were applied in a healthy male Greek 35-years-old, with known natural Mycobacterium tuberculosis primary infection since five years. Skin indurations 72 hours later were 15, 22, 23, 19, 23, and 27 mm respectively. CONCLUSION: No linear relation between tuberculin dose and skin reaction observed; skin reaction increased as tuberculin dose increased but with a decreasing rate, especially after 2 TUs, which seem correctly defined for detection of natural infection. No side-effects occurred. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1186/1757-1626-1-115 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18715513 | - |
| heal.identifier.secondary | http://www.casesjournal.com/content/pdf/1757-1626-1-115.pdf | - |
| heal.journalName | Cases J | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2008 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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