Effect of acute ventricular pressure changes on QRS duration
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Date
Authors
Sideris, D. A.
Toumanidis, S. T.
Kostopoulos, K.
Pittaras, A.
Spyropoulos, G. S.
Kostis, E. B.
Moulopoulos, S. D.
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peer-reviewed
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J Electrocardiol
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Description
The effect of acute changes in ventricular pressure is examined on the QRS duration to clarify the mechanism of ventricular pressure-related arrhythmogenesis. Ventricular pressure was changed acutely by arterial transfusion-bleeding into an open-air ventricular pressure reservoir that was either off or on a metaraminol intravenous drip. While maintaining ventricular pressure at several levels, the QRS duration was measured at 200 mm/s paper speed. The QRS duration correlated significantly with the left ventricular pressure in all 14 dogs examined. An average change in ventricular by 100 mmHg was associated with a change of about 18% in the QRS duration. An acute ventricular pressure elevation impairs the ventricular conduction, which may contribute to ventricular pressure-related arrhythmogenicity.
Description
Keywords
Animals, Aorta/physiopathology, Arrhythmias, Cardiac/*etiology/physiopathology, Blood Pressure/drug effects/physiology, Blood Volume, Dogs, *Electrocardiography/drug effects, Heart Conduction System/drug effects/physiopathology, Infusions, Intravenous, Metaraminol/administration & dosage/pharmacology, Regression Analysis, Tachycardia, Ventricular/etiology/physiopathology, Time Factors, Ventricular Pressure/drug effects/*physiology
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http://www.ncbi.nlm.nih.gov/pubmed/7930981
http://ac.els-cdn.com/S0022073694800022/1-s2.0-S0022073694800022-main.pdf?_tid=e458c436a7952f94647ecc821edf45a0&acdnat=1337847578_d7e78753cd8a99ea3ac3a3be0ea532fe
http://ac.els-cdn.com/S0022073694800022/1-s2.0-S0022073694800022-main.pdf?_tid=e458c436a7952f94647ecc821edf45a0&acdnat=1337847578_d7e78753cd8a99ea3ac3a3be0ea532fe
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en
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Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής