A Novel Semiautomated Atherosclerotic Plaque Characterization Method Using Grayscale Intravascular Ultrasound Images: Comparison With Virtual Histology

dc.contributor.authorAthanasiou, L. S.en
dc.contributor.authorKarvelis, P. S.en
dc.contributor.authorTsakanikas, V. D.en
dc.contributor.authorNaka, K. K.en
dc.contributor.authorMichalis, L. K.en
dc.contributor.authorBourantas, C. V.en
dc.contributor.authorFotiadis, D. I.en
dc.date.accessioned2015-11-24T17:34:53Z
dc.date.available2015-11-24T17:34:53Z
dc.identifier.issn1089-7771-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/14047
dc.rightsDefault Licence-
dc.subjectatherosclerotic plaqueen
dc.subjectplaque characterizationen
dc.subjectvirtual histologyen
dc.subjectlocal binary patternsen
dc.subjectcoronary plaqueen
dc.subjectborder detectionen
dc.subjectarterial-wallen
dc.subjectclassificationen
dc.subjectivusen
dc.subjectsegmentationen
dc.subjectnetworksen
dc.subjectdiseaseen
dc.titleA Novel Semiautomated Atherosclerotic Plaque Characterization Method Using Grayscale Intravascular Ultrasound Images: Comparison With Virtual Histologyen
heal.abstractIntravascular ultrasound (IVUS) virtual histology (VH-IVUS) is a new technique, which provides automated plaque characterization in IVUS frames, using the ultrasound backscattered RF-signals. However, its computation can only be performed once per cardiac cycle (ECG-gated technique), which significantly decreases the number of characterized IVUS frames. Also atherosclerotic plaques in images that have been acquired by machines, which are not equipped with the VH software, cannot be characterized. To address these limitations, we have developed a plaque characterization technique that can be applied in grayscale IVUS images. Our semiautomated method is based on a three-step approach. In the first step, the plaque area [region of interest (ROI)] is detected semiautomatically. In the second step, a set of features is extracted for each pixel of the ROI and in the third step, a random forest classifier is used to classify these pixels into four classes: dense calcium, necrotic core, fibrotic tissue, and fibro-fatty tissue. In order to train and validate our method, we used 300 IVUS frames acquired from virtual histology examinations from ten patients. The overall accuracy of the proposed method was 85.65% suggesting that our approach is reliable and may be further investigated in the clinical and research arena.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDoi 10.1109/Titb.2011.2181529-
heal.identifier.secondary<Go to ISI>://000303997700012-
heal.journalNameIeee Transactions on Information Technology in Biomedicineen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate2012-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Μηχανικών Επιστήμης Υλικώνel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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