A review of drug-induced hyponatremia

dc.contributor.authorLiamis, G.en
dc.contributor.authorMilionis, H.en
dc.contributor.authorElisaf, M. S.en
dc.date.accessioned2015-11-24T19:39:14Z
dc.date.available2015-11-24T19:39:14Z
dc.identifier.issn1523-6838-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/24227
dc.rightsDefault Licence-
dc.subjectAdverse Drug Reaction Reporting Systemsen
dc.subjectFemaleen
dc.subjectGreece/epidemiologyen
dc.subjectHumansen
dc.subjectHyponatremia/*chemically induced/*epidemiologyen
dc.subjectIncidenceen
dc.subjectMaleen
dc.subjectPharmaceutical Preparations/*adverse effectsen
dc.subjectPrognosisen
dc.subjectRisk Assessmenten
dc.subjectSeverity of Illness Indexen
dc.subjectSurvival Analysisen
dc.titleA review of drug-induced hyponatremiaen
heal.abstractHyponatremia (defined as a serum sodium level < 134 mmol/L) is the most common electrolyte abnormality in hospitalized patients. Certain drugs (eg, diuretics, antidepressants, and antiepileptics) have been implicated as established causes of either asymptomatic or symptomatic hyponatremia. However, hyponatremia occasionally may develop in the course of treatment with drugs used in everyday clinical practice (eg, newer antihypertensive agents, antibiotics, and proton pump inhibitors). Physicians may not always give proper attention in time to undesirable drug-induced hyponatremia. Effective clinical management can be handled through awareness of the adverse effect of certain pharmaceutical compounds on serum sodium levels. Here, we review clinical information about the incidence of hyponatremia associated with specific drug treatment and discuss the underlying pathophysiologic mechanisms.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1053/j.ajkd.2008.03.004-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/18468754-
heal.journalNameAm J Kidney Disen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2008-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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