Metabolic syndrome and its components as predictors of ischemic stroke in type 2 diabetic patients
| dc.contributor.author | Protopsaltis, I. | en |
| dc.contributor.author | Korantzopoulos, P. | en |
| dc.contributor.author | Milionis, H. J. | en |
| dc.contributor.author | Koutsovasilis, A. | en |
| dc.contributor.author | Nikolopoulos, G. K. | en |
| dc.contributor.author | Dimou, E. | en |
| dc.contributor.author | Kokkoris, S. | en |
| dc.contributor.author | Brestas, P. | en |
| dc.contributor.author | Elisaf, M. S. | en |
| dc.contributor.author | Melidonis, A. | en |
| dc.date.accessioned | 2015-11-24T19:04:36Z | |
| dc.date.available | 2015-11-24T19:04:36Z | |
| dc.identifier.issn | 1524-4628 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/20070 | |
| dc.rights | Default Licence | - |
| dc.subject | Age Factors | en |
| dc.subject | Aged | en |
| dc.subject | Anthropometry | en |
| dc.subject | Brain Ischemia/*complications | en |
| dc.subject | Diabetes Mellitus, Type 2/*complications | en |
| dc.subject | Female | en |
| dc.subject | Follow-Up Studies | en |
| dc.subject | Humans | en |
| dc.subject | Male | en |
| dc.subject | Metabolic Syndrome X/*complications | en |
| dc.subject | Middle Aged | en |
| dc.subject | Predictive Value of Tests | en |
| dc.subject | Proportional Hazards Models | en |
| dc.subject | Stroke/*etiology | en |
| dc.title | Metabolic syndrome and its components as predictors of ischemic stroke in type 2 diabetic patients | en |
| heal.abstract | BACKGROUND AND PURPOSE: The available data regarding the association between metabolic syndrome (MS) or MS components and ischemic stroke in type 2 diabetics are limited and inconsistent. This study aimed to investigate these associations. METHODS: Five hundred ninety-nine consecutive type 2 diabetic patients (mean age 60.4+/-9.6 years, 54% men) were followed-up for 10.1 years (median period). Baseline clinical and laboratory characteristics and the occurrence of a first-ever ischemic stroke during follow-up were recorded. RESULTS: Seventy-eight patients developed a first-ever ischemic stroke. According to Cox proportional hazard model, waist circumference (hazard ratio, HR:1.006, 95% CI:1.002 to 1.010, P=0.003) and age (HR:1.061, 95% CI:1.002 to 1.125, P=0.04) were significant predictors. After incorporating various combinations of MS components in multivariate models, only age and waist circumference remained significant. CONCLUSIONS: MS per se at baseline or combinations of its components do not predict the development of ischemic stroke in type 2 diabetic patients. Waist circumference represents an independent prognostic factor and could be used as a clinical tool for stroke prevention in this population. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1161/STROKEAHA.107.498311 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/18239165 | - |
| heal.identifier.secondary | http://stroke.ahajournals.org/content/39/3/1036.full.pdf | - |
| heal.journalName | Stroke | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2008 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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