The CSF accumulator: its role in the central nervous system and implications for advancing hydrocephalus shunt technology
| dc.contributor.author | Magram, G. | en |
| dc.contributor.author | Liakos, A. M. | en |
| dc.date.accessioned | 2015-11-24T19:42:11Z | |
| dc.date.available | 2015-11-24T19:42:11Z | |
| dc.identifier.issn | 1016-2291 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/24601 | |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | Cerebrospinal Fluid/*physiology | en |
| dc.subject | Cerebrospinal Fluid Pressure/*physiology | en |
| dc.subject | *Cerebrospinal Fluid Shunts/adverse effects/instrumentation | en |
| dc.subject | Child | en |
| dc.subject | Drainage/adverse effects/instrumentation | en |
| dc.subject | Energy Transfer/physiology | en |
| dc.subject | Fluid Shifts/physiology | en |
| dc.subject | Gravitation | en |
| dc.subject | Homeostasis/*physiology | en |
| dc.subject | Humans | en |
| dc.subject | *Hydrocephalus/cerebrospinal fluid/complications/surgery | en |
| dc.subject | Infant | en |
| dc.subject | Lumbosacral Region | en |
| dc.subject | Posture/physiology | en |
| dc.subject | Prosthesis Design/standards | en |
| dc.subject | Pulsatile Flow/physiology | en |
| dc.subject | Spinal Canal/growth & development | en |
| dc.title | The CSF accumulator: its role in the central nervous system and implications for advancing hydrocephalus shunt technology | en |
| heal.abstract | The 'cerebrospinal fluid (CSF) accumulator' plays an important physiological role in the healthy central nervous system as both a shock absorber and regulator of drainage. In the presence of hydrocephalus, this function is compromised by resistance to the flow of CSF. It is further compromised by the placement of a standard shunt which allows only for one-way directional diversion of the fluid. Complications associated with shunt dependency may be a direct consequence of both the condition, and a failure of existing systems to restore the normal accumulator function. This article reviews the pathophysiology of the 'CSF accumulator' as it relates to hydrocephalus and its management, and proposes a biomimetic shunt designed to restore the 'CSF accumulator' toward normal. It is hoped that such a device will support normalization of intracranial pressure and restore an appropriate level of CSF volume in the shunted patient. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/9440493 | - |
| heal.identifier.secondary | http://content.karger.com/ProdukteDB/produkte.asp?doi=10.1159/000121198 | - |
| heal.journalName | Pediatr Neurosurg | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 1997 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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