Effect of Ethanol on the Sterols of the Fission Yeast Schizosaccharomyces-Pombe

dc.contributor.authorKoukkou, A. I.en
dc.contributor.authorTsoukatos, D.en
dc.contributor.authorDrainas, C.en
dc.date.accessioned2015-11-24T16:56:44Z
dc.date.available2015-11-24T16:56:44Z
dc.identifier.issn0378-1097-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/10478
dc.rightsDefault Licence-
dc.subjectethanol toleranceen
dc.subjectschizosaccharomyces-pombeen
dc.subjectsqualeneen
dc.subjectergosterolen
dc.subjectlanosterolen
dc.subjectmembrane fluidityen
dc.subjectsaccharomyces-cerevisiaeen
dc.subjectplasma-membraneen
dc.subjecttoleranceen
dc.subjectlipidsen
dc.subjectaciden
dc.subjectmetabolismen
dc.subjectalcoholsen
dc.titleEffect of Ethanol on the Sterols of the Fission Yeast Schizosaccharomyces-Pombeen
heal.abstractErgosterol, lanosterol and two further unidentified sterols were detected and quantified in Schizosaccharomyces pombe cell extracts. In cells grown under anaerobic conditions, the levels of these sterols were dramatically reduced with a concomitant increase of their squalene precursor as compared with cells growing under aerobic conditions. Presence of ethanol resulted in a decrease in the sterol content under aerobic conditions. On the contrary, under anaerobic conditions presence of ethanol resulted in a three-fold increase of total sterols. Lanosterol was the main constituent of this elevation. It is suggested that lanosterol in parallel with unsaturated fatty acids is responsible for maintaining membrane integrity of S. pombe cells growing in the presence of ethanol.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://A1993LR79500007-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1574-6968.1993.tb06381.x/asset/j.1574-6968.1993.tb06381.x.pdf?v=1&t=h0dxhbf2&s=73bf1aa57d691a4967ec8e67e8cff9657e885a8c-
heal.journalNameFEMS Microbiol Letten
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate1993-
heal.publisherWiley-Blackwellen
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Θετικών Επιστημών. Τμήμα Χημείαςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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