Subclinical saccadic adduction slowing in patients with monosymptomatic unilateral optic neuritis predicts the development of multiple sclerosis

dc.contributor.authorTsironi, E.en
dc.contributor.authorAnastasopoulos, D.en
dc.contributor.authorLagos, G.en
dc.contributor.authorMergner, T.en
dc.contributor.authorPsilas, K.en
dc.date.accessioned2015-11-24T18:50:07Z
dc.date.available2015-11-24T18:50:07Z
dc.identifier.issn0165-8107-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/18036
dc.rightsDefault Licence-
dc.subjectoptic neuritisen
dc.subjectmultiple sclerosisen
dc.subjectsaccadesen
dc.subjectinternuclear ophthalmoplegiaen
dc.subjecteye-movementsen
dc.subjectfollow-upen
dc.subjectabnormalitiesen
dc.subjectdiagnosisen
dc.subjectbrainen
dc.subjectrisken
dc.titleSubclinical saccadic adduction slowing in patients with monosymptomatic unilateral optic neuritis predicts the development of multiple sclerosisen
heal.abstractParameters of visually guided saccades were studied in 22 patients with monosymptomatic optic neuritis and 21 age-matched control subjects with a precise infrared reflection technique. Follow-up of the patients over 2.2 years, on average, allowed correlations of subclinical saccadic abnormalities, measured at study entry, with the development of clinically definite multiple sclerosis (CDMS). Subclinical adduction slowing defined on statistical grounds was observed in nine patients. Seven of these and four out of five patients with prolonged saccadic latency developed CDMS during the follow-up period. We conclude that subclinical adduction slowing in patients with optic neuritis represents an oculographic finding with pathological significance.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondary<Go to ISI>://000077844900004-
heal.journalNameNeuro-Ophthalmologyen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1998-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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