Diagnostic performance of coronary magnetic resonance angiography as compared against conventional X-ray angiography: a meta-analysis
Φόρτωση...
Ημερομηνία
Συγγραφείς
Danias, P. G.
Roussakis, A.
Ioannidis, J. P.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
J Am Coll Cardiol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
OBJECTIVES: This study was designed to define the current role of coronary magnetic resonance angiography (CMRA) for the diagnosis of coronary artery disease (CAD). BACKGROUND: Coronary magnetic resonance angiography has been proposed as a promising noninvasive method for diagnosis of CAD, but individual studies evaluating its clinical value have been of limited sample size. METHODS: We identified all studies (MEDLINE and EMBASE) that evaluated CAD by both CMRA and conventional angiography in >/=10 subjects during the period 1991 to January 2004. We recorded true and false positive and true and false negative CMRA assessments for detection of CAD using X-ray angiography as the reference standard. Analysis was done at segment, vessel, and subject level. RESULTS: We analyzed 39 studies (41 separate comparisons). Across 25 studies (27 comparisons) with data on 4,620 segments (993 subjects), sensitivity and specificity for detection of CAD were 73% and 86%, respectively. Vessel-level analyses (16 studies, 2,041 vessels) showed sensitivity 75% and specificity 85%. Subject-level analyses (13 studies, 607 subjects) showed sensitivity 88% and specificity 56%. At the segment level, sensitivity was 69% to 79% for all but the left circumflex (61%) coronary artery; specificity was 82% to 91%. There was considerable between-study heterogeneity, but weighted summary receiver-operating characteristic curves agreed with these estimates. There were no major differences between subgroups based on technical or population characteristics, year of publication, reported blinding, or sample size. CONCLUSIONS: In evaluable segments of the native coronary arteries, CMRA has moderately high sensitivity for detecting significant proximal stenoses and may have value for exclusion of significant multivessel CAD in selected subjects considered for diagnostic catheterization.
Περιγραφή
Λέξεις-κλειδιά
Coronary Angiography/*methods, Coronary Artery Disease/*diagnosis, False Positive Reactions, Humans, Image Processing, Computer-Assisted, Magnetic Resonance Angiography/*methods, Radiographic Image Enhancement, Sensitivity and Specificity, X-Rays
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/15519021
http://ac.els-cdn.com/S0735109704016341/1-s2.0-S0735109704016341-main.pdf?_tid=a0183d52508c83c742694422f4c6c8fa&acdnat=1333364398_22ade3188a2f17c640717d05c3138035
http://ac.els-cdn.com/S0735109704016341/1-s2.0-S0735109704016341-main.pdf?_tid=a0183d52508c83c742694422f4c6c8fa&acdnat=1333364398_22ade3188a2f17c640717d05c3138035
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής