Body composition in ambulatory patients with multiple sclerosis

dc.contributor.authorSioka, C.en
dc.contributor.authorFotopoulos, A.en
dc.contributor.authorGeorgiou, A.en
dc.contributor.authorPapakonstantinou, S.en
dc.contributor.authorPelidou, S. H.en
dc.contributor.authorKyritsis, A. P.en
dc.contributor.authorKalef-Ezra, J. A.en
dc.date.accessioned2015-11-24T19:32:39Z
dc.date.available2015-11-24T19:32:39Z
dc.identifier.issn1094-6950-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23436
dc.rightsDefault Licence-
dc.subjectAdipose Tissueen
dc.subjectAdulten
dc.subject*Body Compositionen
dc.subjectBone Densityen
dc.subjectDisease Progressionen
dc.subjectFemaleen
dc.subjectHumansen
dc.subjectMaleen
dc.subjectMiddle Ageden
dc.subjectMultiple Sclerosis/*physiopathologyen
dc.subjectRetrospective Studiesen
dc.subjectYoung Adulten
dc.titleBody composition in ambulatory patients with multiple sclerosisen
heal.abstractThe aim of this study was to compare between ambulatory patients with multiple sclerosis (MS) and control subjects, bone mineral density (BMD), and body composition, that is, percent of bone minerals (M%), fat (F%), and remaining substances (L%). Total body composition and BMD were measured by dual-energy X-ray absorptiometry in 68 patients with definite MS and Expanded Disability Status Scale (EDSS) score </= 6.5 (41 females and 27 males) and 114 control individuals (72 females and 42 males). The amount of F%, L%, M%, and BMD in the whole body, arms, and trunk was not statistically different between MS patients (males and females) and controls, except in the lower extremities of female patients where there was increased F% and reduced L% compared with controls. There were no correlations between F%, L%, M%, and BMD at any anatomic region with EDSS or the cumulative corticosteroid dose. The reduced L% in the lower extremities of female patients suggests a possible increased subsequent risk of osteoporosis in the legs. Brief steroid courses administered during disease exacerbations in ambulatory MS patients did not result in obvious adverse consequences.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1016/j.jocd.2011.04.012-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/21835661-
heal.journalNameJ Clin Densitomen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2011-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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