Neutrophil and monocyte beta 2-integrin expression in trisomic fetuses
dc.contributor.author | Makrydimas, G. | en |
dc.contributor.author | Thilaganathan, B. | en |
dc.contributor.author | Plachouras, N. | en |
dc.contributor.author | Nicolaides, K. H. | en |
dc.date.accessioned | 2015-11-24T19:02:08Z | |
dc.date.available | 2015-11-24T19:02:08Z | |
dc.identifier.issn | 0197-3851 | - |
dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19768 | |
dc.rights | Default Licence | - |
dc.subject | Aneuploidy | en |
dc.subject | Antigens, CD18 | en |
dc.subject | Down Syndrome/immunology | en |
dc.subject | Female | en |
dc.subject | Fetus/*immunology | en |
dc.subject | Flow Cytometry | en |
dc.subject | Humans | en |
dc.subject | Integrins/*biosynthesis | en |
dc.subject | Monocytes/*immunology | en |
dc.subject | Neutrophils/*immunology | en |
dc.subject | Pregnancy | en |
dc.subject | Trisomy/*immunology | en |
dc.title | Neutrophil and monocyte beta 2-integrin expression in trisomic fetuses | en |
heal.abstract | Flow cytometry was used to measure neutrophil and monocyte beta 2-integrin expression in fetuses with trisomy 18 (n = 7) and trisomy 21 (n = 7) at 20-25 weeks' gestation. The values were compared with those of 112 chromosomally normal fetuses. There were no significant differences in beta 2-integrin expression between normal and aneuploid fetuses. These findings demonstrate that in trisomies 21 and 18, alteration in beta 2-integrin expression is unlikely to contribute to the pathogenesis of immunological deficiencies that have been observed in these aneuploidies both prenatally and postnatally. | en |
heal.access | campus | - |
heal.fullTextAvailability | TRUE | - |
heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/7542381 | - |
heal.journalName | Prenat Diagn | en |
heal.journalType | peer-reviewed | - |
heal.language | en | - |
heal.publicationDate | 1995 | - |
heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
heal.type | journalArticle | - |
heal.type.el | Άρθρο Περιοδικού | el |
heal.type.en | Journal article | en |
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