Neutrophil and monocyte beta 2-integrin expression in trisomic fetuses

dc.contributor.authorMakrydimas, G.en
dc.contributor.authorThilaganathan, B.en
dc.contributor.authorPlachouras, N.en
dc.contributor.authorNicolaides, K. H.en
dc.date.accessioned2015-11-24T19:02:08Z
dc.date.available2015-11-24T19:02:08Z
dc.identifier.issn0197-3851-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/19768
dc.rightsDefault Licence-
dc.subjectAneuploidyen
dc.subjectAntigens, CD18en
dc.subjectDown Syndrome/immunologyen
dc.subjectFemaleen
dc.subjectFetus/*immunologyen
dc.subjectFlow Cytometryen
dc.subjectHumansen
dc.subjectIntegrins/*biosynthesisen
dc.subjectMonocytes/*immunologyen
dc.subjectNeutrophils/*immunologyen
dc.subjectPregnancyen
dc.subjectTrisomy/*immunologyen
dc.titleNeutrophil and monocyte beta 2-integrin expression in trisomic fetusesen
heal.abstractFlow cytometry was used to measure neutrophil and monocyte beta 2-integrin expression in fetuses with trisomy 18 (n = 7) and trisomy 21 (n = 7) at 20-25 weeks' gestation. The values were compared with those of 112 chromosomally normal fetuses. There were no significant differences in beta 2-integrin expression between normal and aneuploid fetuses. These findings demonstrate that in trisomies 21 and 18, alteration in beta 2-integrin expression is unlikely to contribute to the pathogenesis of immunological deficiencies that have been observed in these aneuploidies both prenatally and postnatally.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/7542381-
heal.journalNamePrenat Diagnen
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate1995-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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