Breastfeeding and vitamin D status in Greece during the first 6 months of life
| dc.contributor.author | Challa, A. | en |
| dc.contributor.author | Ntourntoufi, A. | en |
| dc.contributor.author | Cholevas, V. | en |
| dc.contributor.author | Bitsori, M. | en |
| dc.contributor.author | Galanakis, E. | en |
| dc.contributor.author | Andronikou, S. | en |
| dc.date.accessioned | 2015-11-24T19:32:13Z | |
| dc.date.available | 2015-11-24T19:32:13Z | |
| dc.identifier.issn | 0340-6199 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/23381 | |
| dc.rights | Default Licence | - |
| dc.subject | Adult | en |
| dc.subject | *Breast Feeding | en |
| dc.subject | Female | en |
| dc.subject | Greece/epidemiology | en |
| dc.subject | Humans | en |
| dc.subject | Infant | en |
| dc.subject | Infant, Newborn | en |
| dc.subject | Prospective Studies | en |
| dc.subject | Reference Values | en |
| dc.subject | Seasons | en |
| dc.subject | Vitamin D/*analogs & derivatives/blood | en |
| dc.subject | Vitamin D Deficiency/*epidemiology | en |
| dc.title | Breastfeeding and vitamin D status in Greece during the first 6 months of life | en |
| heal.abstract | Since no foods are vitamin D supplemented in Greece, vitamin D status was assessed in mothers at birth and their infants up to the first 6 months of life, while they were exclusively breast-fed. This was a prospective study. Full-terms (n =35) born during the summer-autumn months and their mothers were assigned to the summer group and the remainder (n =31) to the winter group. One week after birth, serum 25-hydroxyvitamin D (25OHD) was significantly lower in the winter-born than in the summer-born neonates (6.7+/-0.7 vs. 10.1+/-0.9 ng/ml, P <0.01). The respective levels of parathyroid hormone (iPTH) were 64.9+/-13.4 and 33.9+/-4.4 pg/ml (P <0.01). The mothers had serum 25OHD levels of 10.8+/-1.0 ng/ml and iPTH levels of 15.2+/-3.5 pg/ml in the winter and 12.9+/-1.3 ng/ml and 24.8+/-4.8 pg/ml in the summer. During the 6-month follow-up, a steady increase in circulating 25OHD (up to 19.4+/-2.8 ng/ml, P <0.0001) and a decrease in iPTH (to 26.8+/-3.5 pg/ml, P =0.10) were observed in the infants born in the winter. In the summer-born infants, serum 25OHD did not change but iPTH had increased significantly by the 3rd month (59.4+/-21.8, P <0.05). Serum calcium (Ca) increased within normal limits during the study period in both groups. Serum phosphorus (Pi) started higher in the winter group (7.43+/-0.38 vs. 6.27+/-0.23 mg/dl, P <0.01) but thereafter, it was similar in both groups. Total alkaline phosphatase (ALP) increased in both groups during the study (164+/-15 vs. 219+/-17 IU/l, P <0.05 and 189+/-14 vs. 288+/-35 IU/l, P <0.001, respectively). Serum osteocalcin (OC) decreased in the winter-born neonates (32.0+/-3.4 vs. 21.5+/-3.4 ng/ml, P <0.05) and did not change in the summer group (28.9+/-3.5 vs. 26.5+/-2.8 ng/ml). CONCLUSION: Neonates who are breast-fed exclusively during the first 6 months of life are in need of vitamin D supplementation irrespective of the season even in a sunny country like Greece where foods are not supplemented. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.primary | 10.1007/s00431-005-1757-1 | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/16143866 | - |
| heal.identifier.secondary | http://www.springerlink.com/content/v712903115476726/fulltext.pdf | - |
| heal.journalName | Eur J Pediatr | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2005 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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