Periocular xanthogranuloma: A forgotten entity?
| dc.contributor.author | Papagoras, C. | en |
| dc.contributor.author | Kitsos, G. | en |
| dc.contributor.author | Voulgari, P. V. | en |
| dc.contributor.author | Zikou, A. K. | en |
| dc.contributor.author | Argyropoulou, M. I. | en |
| dc.contributor.author | Zioga, A. | en |
| dc.contributor.author | Drosos, A. A. | en |
| dc.date.accessioned | 2015-11-24T18:59:36Z | |
| dc.date.available | 2015-11-24T18:59:36Z | |
| dc.identifier.issn | 1177-5483 | - |
| dc.identifier.uri | https://olympias.lib.uoi.gr/jspui/handle/123456789/19384 | |
| dc.rights | Default Licence | - |
| dc.title | Periocular xanthogranuloma: A forgotten entity? | en |
| heal.abstract | Periocular xanthogranulomatous diseases are a rare group of disorders which are characterized by a predilection to affect the orbit and ocular adnexa and special histopathological features, in particular infiltrates comprising non-Langerhans-derived foamy histiocytes and Touton giant cells. The differential diagnosis is difficult and occasionally definite diagnosis cannot be established even after clinical and histopathological findings are taken together. We describe a case of a middle-aged man who presented with a 10-year history of voluminous eyelid swelling with concomitant late-onset atopic manifestations, namely bronchial asthma and allergic rhinitis with nasal polyps. After thorough clinical and laboratory investigation, including a biopsy of the eyelid, we classified the patient's disease to a rare entity that has been relatively recently described: periocular xanthogranuloma associated with adult-onset asthma. In a review of the literature, no prospective trials concerning the treatment of this disease were found. The literature mainly contained case reports and case series in which corticosteroids and chemotherapy with alkylating agents have been reported to be beneficial. We treated our patient with a combination of oral corticosteroids and cyclophosphamide pulses and we observed substantial regression of the eyelid masses together with a normalization of systemic immunologic abnormalities. | en |
| heal.access | campus | - |
| heal.fullTextAvailability | TRUE | - |
| heal.identifier.secondary | http://www.ncbi.nlm.nih.gov/pubmed/20234776 | - |
| heal.journalName | Clin Ophthalmol | en |
| heal.journalType | peer-reviewed | - |
| heal.language | en | - |
| heal.publicationDate | 2010 | - |
| heal.recordProvider | Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής | el |
| heal.type | journalArticle | - |
| heal.type.el | Άρθρο Περιοδικού | el |
| heal.type.en | Journal article | en |
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