Carcinoembryonic antigen (CEA) in normal and pre-eclamptic pregnancies (values in maternal blood, amniotic fluid and umbilical cord blood)
Φόρτωση...
Ημερομηνία
Συγγραφείς
Messinis, I. E.
Milingos, S.
Lolis, D.
Diakomanolis, E.
Antoniou, K.
Chrysikou, M.
Kaskarelis, D.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Eur J Obstet Gynecol Reprod Biol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
Values of carcinoembryonic antigen (CEA) were measured by radioimmunoassay in 100 pregnant women divided into 4 groups. In group 1 (49 normal pregnancies) and 2 (17 pre-eclamptic pregnancies), the estimation of CEA was done in maternal vein blood, umbilical cord blood and in amniotic fluid. In group 3 (20 normal pregnancies) CEA was measured separately in blood of the two umbilical vessels as well as in maternal vein blood. In group 4 (14 pregnancies with small-for-date infants) CEA was estimated in umbilical cord blood. The values in amniotic fluid of normal and pre-eclamptic pregnancies were more than 20 times higher than in the other two compartments. A significant correlation was found between the amniotic fluid and umbilical cord blood values (r = 0.500; P < 0.05), as well as between the values in umbilical artery and vein (r = 0.792; P < 0.001). Thus, it is thought that CEA is transferred from the amniotic cavity to the umbilical cord while a part of CEA perhaps is produced by the placenta. Umbilical cord blood values of small-for-date fetuses do not differ significantly from the normal. On the contrary, significantly lower values were obtained in umbilical cord blood and in amniotic fluid of pre-eclamptic women as compared to the normal, but this finding is not useful clinically because of the large standard deviation.
Περιγραφή
Λέξεις-κλειδιά
Amniotic Fluid/*analysis, Carcinoembryonic Antigen/*analysis/metabolism, Female, Fetal Blood/*analysis, Fetal Distress/diagnosis, Humans, Infant, Newborn, Meconium, Pre-Eclampsia/*blood, *Pregnancy, Radioimmunoassay, Umbilical Arteries, Umbilical Veins
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/7190518
http://ac.els-cdn.com/0028224380900842/1-s2.0-0028224380900842-main.pdf?_tid=2e7bfe81394b70037e1284ea2f615314&acdnat=1332926136_5f5ed5c468c691f8326bc891a7c3349f
http://ac.els-cdn.com/0028224380900842/1-s2.0-0028224380900842-main.pdf?_tid=2e7bfe81394b70037e1284ea2f615314&acdnat=1332926136_5f5ed5c468c691f8326bc891a7c3349f
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής