Involvement of phospholipids in apolipoprotein B modification during low density lipoprotein oxidation

dc.contributor.authorKarakatsani, A. I.en
dc.contributor.authorLiapikos, T. A.en
dc.contributor.authorTroganis, A. N.en
dc.contributor.authorTsoukatos, D. C.en
dc.date.accessioned2015-11-24T16:31:58Z
dc.date.available2015-11-24T16:31:58Z
dc.identifier.issn0024-4201-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/7501
dc.rightsDefault Licence-
dc.subjectplatelet-activating-factoren
dc.subjectpaf-degrading acetylhydrolaseen
dc.subjecthuman-plasmaen
dc.subjectlipid-peroxidationen
dc.subjectldlen
dc.subjectdegradationen
dc.subjectcholesterolen
dc.subjectreceptoren
dc.subjectphosphatidylcholineen
dc.subjectrecognitionen
dc.titleInvolvement of phospholipids in apolipoprotein B modification during low density lipoprotein oxidationen
heal.abstractAn increased amount of phospholipids remained attached on delipidated apolipoprotein B originated from oxidized low density lipoprotein (LDL). P-31 nuclear magnetic resonance analysis of such apolipoprotein showed an organic phosphorus peak at -0.55 ppm, which suggests the formation of adducts (most probably Schiff bases) of oxidized phospholipids with apolipoprotein B. The above reaction occurs in parallel with the hydrolysis of oxidized phospholipids, catalyzed by the LDL-attached platelet-activating factor acetylhydrolase, and may contribute to the proatherogenic effect of oxidatively modified low density lipoprotein.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primaryDOI 10.1007/s11745-998-0318-3-
heal.identifier.secondary<Go to ISI>://000078100700002-
heal.journalNameLipidsen
heal.journalTypepeer reviewed-
heal.languageen-
heal.publicationDate1998-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών και Τεχνολογιών. Τμήμα Βιολογικών Εφαρμογών και Τεχνολογιώνel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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