Comparison of coronary collateral circulation in diabetic and nondiabetic patients suffering from coronary artery disease
Φόρτωση...
Ημερομηνία
Συγγραφείς
Melidonis, A.
Tournis, S.
Kouvaras, G.
Baltaretsou, E.
Hadanis, S.
Hajissavas, I.
Tsatsoulis, A.
Foussas, S.
Τίτλος Εφημερίδας
Περιοδικό ISSN
Τίτλος τόμου
Εκδότης
Περίληψη
Τύπος
Είδος δημοσίευσης σε συνέδριο
Είδος περιοδικού
peer-reviewed
Είδος εκπαιδευτικού υλικού
Όνομα συνεδρίου
Όνομα περιοδικού
Clin Cardiol
Όνομα βιβλίου
Σειρά βιβλίου
Έκδοση βιβλίου
Συμπληρωματικός/δευτερεύων τίτλος
Περιγραφή
BACKGROUND AND HYPOTHESIS: Although it is well established that diabetes mellitus (DM) induces more severe coronary artery disease (CAD), it is not known whether it contributes to the development of coronary collateral circulation. The present study examines coronary collateral circulation in diabetic and nondiabetic patients with angiographically verified CAD. METHODS: The study group consisted of 463 diabetic patients (382 men, 81 women) with a mean age of 60.3 +/- 8.8 years, and 227 nondiabetic subjects (159 men, 68 women) with a mean age of 59.2 +/- 9 years. The extension and functional capacity of coronary collateral circulation was assessed according to the Cohen and Rentrop grading system of 0 to III. RESULTS: We found that diabetic patients had grade III collateral circulation more frequently than nondiabetic subjects (13.2 vs. 8.5%, p < 0.01). This finding was even more pronounced in diabetic men aged < 55 years compared with both nondiabetic men (20 vs. 3.4%, p < 0.001) and diabetic women (20 vs. 2.2%, p < 0.001). Grade III collateral circulation was found to develop mainly at the left anterior descending (LAD) coronary artery and the right coronary artery (RCA), where complete occlusions of coronary arteries usually occur. CONCLUSIONS: Diabetic patients with CAD develop more extensive coronary collateral circulation than nondiabetic subjects, especially men aged < 55 years. The collateral circulation mainly develops at the LAD and RCA.
Περιγραφή
Λέξεις-κλειδιά
Adult, Aged, Aged, 80 and over, *Collateral Circulation, *Coronary Circulation, Coronary Disease/complications/*physiopathology, Diabetes Complications, Diabetes Mellitus/*physiopathology, Female, Humans, Male, Middle Aged, Prospective Studies, Risk Factors
Θεματική κατηγορία
Παραπομπή
Σύνδεσμος
http://www.ncbi.nlm.nih.gov/pubmed/10410290
http://onlinelibrary.wiley.com/store/10.1002/clc.4960220706/asset/4960220706_ftp.pdf?v=1&t=h0ouhp3m&s=f6e28831b2e701f22d2f1c2210590afa11fa2545
http://onlinelibrary.wiley.com/store/10.1002/clc.4960220706/asset/4960220706_ftp.pdf?v=1&t=h0ouhp3m&s=f6e28831b2e701f22d2f1c2210590afa11fa2545
Γλώσσα
en
Εκδίδον τμήμα/τομέας
Όνομα επιβλέποντος
Εξεταστική επιτροπή
Γενική Περιγραφή / Σχόλια
Ίδρυμα και Σχολή/Τμήμα του υποβάλλοντος
Πανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικής