Clinical management of HPV-related disease of the lower genital tract

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dc.contributor.authorKyrgiou, M.en
dc.contributor.authorValasoulis, G.en
dc.contributor.authorFounta, C.en
dc.contributor.authorKoliopoulos, G.en
dc.contributor.authorKarakitsos, P.en
dc.contributor.authorNasioutziki, M.en
dc.contributor.authorNavrozoglou, I.en
dc.contributor.authorDalkalitsis, N.en
dc.contributor.authorParaskevaidis, E.en
dc.date.accessioned2015-11-24T19:30:19Z
dc.date.available2015-11-24T19:30:19Z
dc.identifier.issn1749-6632-
dc.identifier.urihttps://olympias.lib.uoi.gr/jspui/handle/123456789/23067
dc.rightsDefault Licence-
dc.subjectAlgorithmsen
dc.subjectAlphapapillomavirus/*physiologyen
dc.subjectCervical Intraepithelial Neoplasia/diagnosis/rehabilitation/therapyen
dc.subjectCytodiagnosis/methodsen
dc.subjectFemaleen
dc.subjectGenital Diseases, Female/*etiology/rehabilitation/*therapyen
dc.subjectHumansen
dc.subjectMass Screening/methodsen
dc.subjectPapillomavirus Infections/etiology/*therapyen
dc.subjectUterine Cervical Neoplasms/diagnosis/rehabilitation/therapyen
dc.titleClinical management of HPV-related disease of the lower genital tracten
heal.abstractCytology remains the mainstay for cervical screening. The need to achieve effective management, limit complications, and preserve reproductive function led to the popularity of local treatment. Although the cure rates for ablative and excisional methods are similar, the excisional method provides a more reliable histopathological diagnosis. Recent evidence revealed increased perinatal morbidity after treatment that appears to be related to the proportion of cervix removed. The human papillomavirus (HPV) DNA test appears to enhance the detection of disease in primary screening, in the triage of minor cytological abnormalities, and in follow-up. Further research on the clinical application of a scoring system is ongoing. The vaccines are now available and appear to be safe, well tolerated, and highly efficacious in HPV naive women. A synergy of vaccination and screening will be required. Treatment for early cervical cancer is increasingly shifting toward more fertility-sparing surgical techniques. Careful selection of patients is essential.en
heal.accesscampus-
heal.fullTextAvailabilityTRUE-
heal.identifier.primary10.1111/j.1749-6632.2010.05676.x-
heal.identifier.secondaryhttp://www.ncbi.nlm.nih.gov/pubmed/20840254-
heal.identifier.secondaryhttp://onlinelibrary.wiley.com/store/10.1111/j.1749-6632.2010.05676.x/asset/j.1749-6632.2010.05676.x.pdf?v=1&t=h0p6rmw2&s=b6244c47fc9c1345ea57f00f1f31e917f6a925f4-
heal.journalNameAnn N Y Acad Scien
heal.journalTypepeer-reviewed-
heal.languageen-
heal.publicationDate2010-
heal.recordProviderΠανεπιστήμιο Ιωαννίνων. Σχολή Επιστημών Υγείας. Τμήμα Ιατρικήςel
heal.typejournalArticle-
heal.type.elΆρθρο Περιοδικούel
heal.type.enJournal articleen

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